Results 111 to 120 of about 244,605 (365)

Rab GTPases: Switching to Human Diseases

open access: yesCells, 2019
Rab proteins compose the largest family of small GTPases and control the different steps of intracellular membrane traffic. More recently, they have been shown to also regulate cell signaling, division, survival, and migration.
N. A. Guadagno, C. Progida
semanticscholar   +1 more source

PERENCANAAN ULANG PONDASI BORE PILE DITINJAU DARI SEGI BIAYA PADA PROYEK TRANSMISI 500 KV SUMATERA PAKET 2, PERANAP – PERAWANG PROVINSI RIAU

open access: yesJurnal Teknik, 2017
PT. Waskita Karya (Persero) Tbk, mengerjakan proyek pembanguanan transmisi 500 kV Sumatera paket 2, Peranap – Perawang di Provinsi Riau. Yang akan direncanakan di 3 (tiga) Kabupaten dengan panjang 160 Kilometer, dan terdiri dari 377 tower.
Mario Pratama   +2 more
doaj  

The nuts and bolts of the platelet release reaction

open access: yesPlatelets, 2017
Secretion is essential to many of the roles that platelets play in the vasculature, e.g., thrombosis, angiogenesis, and inflammation, enabling platelets to modulate the microenvironment at sites of vascular lesions with a myriad of bioactive molecules ...
Smita Joshi, Sidney W. Whiteheart
doaj   +1 more source

The Real Price of College: College Completion Series: Part Two [PDF]

open access: yes, 2016
The high price of college is the subject of media headlines, policy debates, and dinner table conversations because of its implications for educational opportunities, student and family pocketbooks, and the economy. Some people caution against giving too
Nancy Kendall, Sara Goldrick-Rab
core  

CCN1 Enhances Tumor Immunosuppression through Collagen‐Mediated Chemokine Secretion in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
CCN1 modulates the tumor microenvironment in pancreatic cancer by promoting collagen‐dependent chemokine production, thereby facilitating immune evasion. Deletion of CCN1 not only suppresses tumor growth but also enhances immune cell infiltration and increases tumor sensitivity to both chemotherapy and immunotherapy.
Hongjie Fan   +9 more
wiley   +1 more source

Hepatitis B virus movement through the hepatocyte: An update

open access: yesBiology of the Cell, Volume 114, Issue 12, Page 325-348, December 2022., 2022
Model of intracellular trafficking routes of progeny hepatitis B virus (HBV) viral and subviral particles through the liver cell involving nucleocytoplasmic shuttling, movement through the ER/Golgi secretory pathway, and budding and release through the multivesicular body (MVB) and/or secretory autophagosomes (sAP) axis.
Reinhild Prange
wiley   +1 more source

Comprehensive knockout analysis of the Rab family GTPases in epithelial cells

open access: yesJournal of Cell Biology, 2019
Rab small GTPases (∼60 genes in mammals) are the master regulators of intracellular membrane trafficking. Homma et al. establish a comprehensive collection of knockout epithelial cell lines for all the mammalian Rabs, revealing that Rab6 is required for ...
Y. Homma   +8 more
semanticscholar   +1 more source

Addressing the paradox – the divergence between smallholders’ preference and actual adoption of agricultural innovations

open access: yesInternational Journal of Agricultural Sustainability, 2018
Experiences in smallholder contexts indicate frequent mismatches between technologies introduced and needs of farmers who must make complex decisions in reallocating their limited resources under highly risky ecological and market contexts.
Miyuki Iiyama   +8 more
doaj   +1 more source

Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu   +8 more
wiley   +1 more source

Rab(ble) rouser [PDF]

open access: yesThe Journal of Cell Biology, 2008
It takes more than one inhibitor to keep a Rab down, Brett et al. report. The team determined that yeast cells use two switches to turn off this vesicle management protein. Figure 1 When yeast cells overproduce the Rab blocker Gyp7, their vacuoles fragment (right). The Rab proteins regulate the transport and fusion of vesicles.
openaire   +2 more sources

Home - About - Disclaimer - Privacy