Results 121 to 130 of about 2,160,348 (358)
, 1999 Excerpt: In counterconditioning a maladaptive response is eliminated by establishing a new response in the presence of the stimulus that initially controlled occurrence of the maladaptive response. In a classical study crying in the presence of a rabbit
Bufford, Rodger K.
core
Rabbit production in low-input systems in Africa: situation, knowledge and perspectives – A review
, 2014 High poverty levels continue to plague much of Africa despite several intervention strategies aimed to stem the tide. The role of small livestock like rabbits as a tool in poverty alleviation programmes has been acknowledged for decades and successful ...
Saheed Oluwasina Oseni, S. Lukefahr
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Beni-Suef University Journal of Basic and Applied SciencesBackground The global poultry industry has been experiencing increasing condemnation at slaughterhouses since 2011, due to the emergence of avian reovirus (ARV) variant strains.
Eslam Arafa +6 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Rabbit models of heart disease. [PDF]
, 2008 Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core
Detection of antibodies to Sendai virus by enzyme-linked immunosorbent assay (ELISA) [PDF]
, 1979 An enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to Sendai virus, a paramyxovirus, is described. The assay was found to be about 20-fold more sensitive than the hemagglutination inhibition assay.
Avrameas +17 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Effect of artificial warren size on a restocked European wild rabbit population [PDF]
, 2017 From the time since the decline of the wild rabbit Oryctolagus cuniculus in southern Europe, various techniques and methods have been explored with a view to restoring wild rabbit populations or increasing rabbit resilience, for both conservation and ...
Castro, Francisca +3 more
core +1 more source