Results 121 to 130 of about 1,118,487 (315)

Abstracts of the communications presented during the 9th French Rabbit Days.Paris, November 28-29th, 2001: NUTRITION

, 2001
World Rabbit Science (2001). Abstracts of the communications presented during the 9th French Rabbit Days.Paris, November 28-29th, 2001: NUTRITION. World Rabbit Science. 9.
World Rabbit Science, NUTRITION,
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

INFLUENCE OF COSTUS ROOTS EXTRACT ON PRODUCTIVE PERFORMANCE, PHYSIOLOGICAL RESPONSES AND BACTERIAL COUNT IN WEANING RABBITS [PDF]

Egyptian Journal of Rabbit Science
The current investigation began at a private rabbitry farm in Qalyubia province, Egypt's during winter season. The study aimed to investigate the Saussurea lappa effects on productive performance, digestibility and biochemical blood of weaning rabbits ...
Mohamed Elsawy, Mohamed elspeiy, Tarek Sadaka, Mohamed Abdella, Mahmoud Habib, Bahaa Abou-Shehema, Hossam Shahba   +6 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Abstracts of the communications presented during the 9th French Rabbit Days. Paris, November 28-29th 2001: PATHOLOGY

, 2001
World Rabbit Science (2001). Abstracts of the communications presented during the 9th French Rabbit Days. Paris, November 28-29th 2001: PATHOLOGY. World Rabbit Science. 9.
PATHOLOGY,, World Rabbit Science
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Abstracts of the communications presented during the 8th French Rabbit Days: Table of contents

, 1999
World Rabbit Science (1999). Abstracts of the communications presented during the 8th French Rabbit Days: Table of contents. World Rabbit Science. 07.
World Rabbit Science, Table of Contents,
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MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

EVALUATION OF ANTIVIRAL AND ANTIBACTERIAL ACTIVITY OF SOME ESSENTIAL OILS AGAINST NEWCASTLE DISEASE VIRUS, SALMONELLA TYPHIMURIUM AND ESCHERICHIA COLI [PDF]

Assiut Veterinary Medical Journal
Background: Due to their potential for treating a variety of common illnesses, medicinal plants have recently attracted a lot of attention, also other medicinal assertions are now supported by a wealth of scientific evidence, so nowadays natural products
AYA ABDEL-MOHSEN, OMAR AMEN, RAGAB IBRAHIM, MARWA ALI, MOHAMED HAMZA, YASMIN SADIEK   +5 more
doaj   +1 more source