Results 191 to 200 of about 3,667 (257)

TALEN/CRISPR-mediated eGFP knock-in add-on at the OCT4 locus does not impact differentiation of human embryonic stem cells towards endoderm. [PDF]

PLoS One, 2014
Krentz NA, Nian C, Lynn FC.
europepmc   +1 more source

Ag‐Cu Nanoarchitecture for Enhanced LSPR Absorption: the Role of Surface Roughness and near‐field Interactions

Advanced Materials Interfaces, EarlyView.
This study investigates the plasmonic properties and biosensing capabilities of a nanocomposite incorporating Cu and Ag nanoparticles for detecting anti‐DbpA antibodies associated with Lyme disease. The enhanced LSPR response is explained through FDTD simulations of Cu–Ag near‐field interactions and increased surface roughness.
Sanjay Kumar, Pavel Curda, Hana Maskova, Lenka Doudová, Pavel Pleskunov, Anna Kuzminova, Libor Hejduk, Jan Sterba, Ondřej Kylián, Ryan O. M. Rego, Vitezslav Stranak   +10 more
wiley   +1 more source

Motor neuron activation in peripheral nerves using infrared neural stimulation. [PDF]

J Neural Eng, 2014
Peterson EJ, Tyler DJ.
europepmc   +1 more source

Using QCM‐D for Real‐Time Analysis of Cell Adhesion Dynamics at Biointerfaces

Advanced Materials Interfaces, EarlyView.
This study explores adhesion of human fibroblasts to functionalized biomaterial surfaces. Quartz crystal microbalance with dissipation (QCM‐D) is used to measure cell responses in real time. The QCM‐D signalis correlated with changes in cell morphology and focal adhesion kinase (FAK) activation. This data shows a positive correlation between the energy
Agnes Rogala, Hanna Tiainen, Daria Zaytseva‐Zotova   +2 more
wiley   +1 more source

Multiplexed Bio‐detection on an Interferometric Optical Waveguide Assembly

Advanced Materials Interfaces, EarlyView.
Multiplexed remote bio‐detection is demonstrated through an image conduit composed of 3012 individual cores and coated with interferometric layers. The proof of concept of biodetection is performed through the kinetic monitoring of two complementary DNA strands hybridization paving the way for applications in multiplex in situ biosensing, and ...
Oleksii Bratash, Rémi Courson, Laurent Malaquin, Thierry Leichle, Arnaud Buhot, Loïc Leroy, Elodie Engel   +6 more
wiley   +1 more source

Uncovering pharmacological mechanisms of Wu-tou decoction acting on rheumatoid arthritis through systems approaches: drug-target prediction, network analysis and experimental validation. [PDF]

Sci Rep, 2015
Zhang Y, Bai M, Zhang B, Liu C, Guo Q, Sun Y, Wang D, Wang C, Jiang Y, Lin N, Li S.   +10 more
europepmc   +1 more source

ESCRT III Regulates Lysosomal Perinuclear Clustering by Inhibiting Kinesin 1 Leading to Agnps Cytotoxicity in Human Cells

Advanced Materials Interfaces, EarlyView.
AgNPs cause significant damage upon entering the lysosomes of human fibroblasts, resulting in lysosomal transport disorders and the occurrence of perinuclear clustering (LPC) of lysosomes by promoting apoptosis that is accompanied by a reduction in the expression levels of ESCRT III and Kinesin 1 proteins.
Tiantian Liu, Aiguo Xie, Chao Xing, RuiZhe He, Wei Ni, Yinbo Peng, Peng Xu, Yong Fang   +7 more
wiley   +1 more source

Aqueous Synthesis of Poly(ethylene glycol)‐Amide‐Norbornene‐Carboxylate for Modular Hydrogel Crosslinking

Advanced Materials Interfaces, EarlyView.
An all aqueous synthesis of poly(ethylene glycol)‐amide‐norbornene‐carboxylate (PEGaNBCA) is developed via reacting carbic anhydride with amino‐terminated PEG. PEGaNBCA is readily crosslinked into hydrogels by click chemistries. PEGaNBCA crosslinked thiol‐norbornene hydrogels are hydrolytically stable but can be rendered hydrolytically labile through ...
Nathan H. Dimmitt, Chien‐Chi Lin
wiley   +1 more source

Pathway of PPAR-gamma coactivators in thermogenesis: a pivotal traditional Chinese medicine-associated target for individualized treatment of rheumatoid arthritis. [PDF]

Oncotarget, 2016
Zhang Y, Mao X, Guo Q, Bai M, Zhang B, Liu C, Sun Y, Li S, Lin N.   +8 more
europepmc   +1 more source

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source