Results 41 to 50 of about 171,892 (231)

Abstracts of the communications presented during the 9th French Rabbit Days: GROWTH AND MEAT [PDF]

open access: yes, 2001
World Rabbit Science (2001). Abstracts of the communications presented during the 9th French Rabbit Days: GROWTH AND MEAT. World Rabbit Science. 9.
GROWTH AND MEAT,, World Rabbit Science
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Abstracts of the communications presented during the 9th French Rabbit Days. Paris, November 28-29th 2001. SEVRAGE WEANING [PDF]

open access: yes, 2001
World Rabbit Science (2001). Abstracts of the communications presented during the 9th French Rabbit Days. Paris, November 28-29th 2001. SEVRAGE WEANING. World Rabbit Science. 9.
World Rabbit Science, SEVRAGE WEANING,
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Abstracts of the communications presented during the 9th French Rabbit Days. Paris, November 28-29th 2001:ECONOMY- GENETICS [PDF]

open access: yes, 2001
World Rabbit Science (2001). Abstracts of the communications presented during the 9th French Rabbit Days. Paris, November 28-29th 2001:ECONOMY- GENETICS. World Rabbit Science. 9.
ECONOMY- GENETICS,, World Rabbit Science
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

ABSTRACTS OF 3rd INTERNATIONAL MEETING ON RABBIT BIOTECHNOLOGY: XI'AN, CHINA, JUNE 2009 [PDF]

open access: yes, 2009
[EN] As many of you have known, the investigations of biological functions of genes and proteins and their relationship with the pathogenesis of human diseases requires appropriate and relevant animal models. Although mice (wild and genetically modified)
XI'AN, CHINA, JUNE 2009,   +1 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Abstracts of the "21st Hungary conference on rabbit production" Kaposvár, Hungary. May 27, 2009 [PDF]

open access: yes, 2010
[EN] About 90 participants took part at the 21st Hungarian Conference on Rabbit Production at Kaposvár, organized by the University of Kaposvár, the Hungarian Branch of the WRSA, the Rabbit Production Board and the Agribrands Europe Hungary Inc.
World Rabbit Science   +1 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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