Results 201 to 210 of about 5,330,187 (273)

Emergence of a new lagovirus related to Rabbit Haemorrhagic Disease Virus. [PDF]

open access: yesVet Res, 2013
Le Gall-Reculé G   +13 more
europepmc   +1 more source

Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy

open access: yesiMeta, Volume 5, Issue 5, October 2026.
A prognosis‐oriented classification system was established to distinguish Pachy PCV from Non‐pachy PCV using a large multicenter dataset. Comparative plasma multi‐omics profiling of Pachy PCV, Non‐pachy PCV, and normal controls revealed unique upregulation of the fluid shear stress and atherosclerosis (FSS‐AS) and HIF‐1 signaling pathways in Pachy PCV.
Xinyu Zhao   +18 more
wiley   +1 more source

Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis

open access: yesLasers in Surgery and Medicine, Volume 58, Issue 8, Page 644-655, October 2026.
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran   +7 more
wiley   +1 more source

Clinical and Histopathological Evaluation of Maximal and Supramaximal Energy Direct Selective Laser Trabeculoplasty (DSLT): A Rabbit Model Safety Study

open access: yesLasers in Surgery and Medicine, Volume 58, Issue 8, Page 693-703, October 2026.
ABSTRACT Objectives This study aimed to assess the clinical and histopathological effects of maximal available and supramaximal energy exposure in direct selective laser trabeculoplasty (DSLT®) on target and nontarget ocular tissues compared with selective laser trabeculoplasty (SLT) and sham treatments.
Liat Mendel Veig   +4 more
wiley   +1 more source

Blocking Extracellular Cyclophilin A‐Mediated Adhesion Protects Against Bacterial Infection

open access: yesMedComm, Volume 7, Issue 10, October 2026.
eCypA promotes bacterial infection by upregulating TGF‐β signaling‐dependent adhesion receptor expression. Pathogens such as IAV, GAS, S. P., and K. P. induce eCypA secretion. Binding of eCypA with TβR2 enhances the affinity of TGF‐β1 and TβR2, which positively regulates adhesion receptors expression via the TGF‐β/Smad signaling pathway, thereby ...
Xiaoyuan Bai   +16 more
wiley   +1 more source

Mechanistic Evaluation of Luteolin in Wound Healing of Diabetic Foot Ulcer via Nrf2 Signaling

open access: yesPhytotherapy Research, Volume 40, Issue 10, Page 5901-5917, October 2026.
Proposed mechanism by which Luteolin (LU) promotes diabetic foot ulcer healing. LU attenuates hyperglycemia‐induced oxidative stress and lipid peroxidation, improves endothelial cell viability, and suppresses ferroptosis through Nrf2‐dependent antioxidant signaling, thereby accelerating angiogenesis and wound repair. ABSTRACT Diabetic foot ulcers (DFUs)
Muhammed Yusuf   +2 more
wiley   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

open access: yesActa Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, restores blood–brain barrier integrity in a human stem cell‐based model of ischaemic stroke

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5791-5812, October 2026.
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó   +14 more
wiley   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

open access: yesJournal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy