Results 201 to 210 of about 5,330,187 (273)
Emergence of a new lagovirus related to Rabbit Haemorrhagic Disease Virus. [PDF]
Le Gall-Reculé G +13 more
europepmc +1 more source
Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy
A prognosis‐oriented classification system was established to distinguish Pachy PCV from Non‐pachy PCV using a large multicenter dataset. Comparative plasma multi‐omics profiling of Pachy PCV, Non‐pachy PCV, and normal controls revealed unique upregulation of the fluid shear stress and atherosclerosis (FSS‐AS) and HIF‐1 signaling pathways in Pachy PCV.
Xinyu Zhao +18 more
wiley +1 more source
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran +7 more
wiley +1 more source
ABSTRACT Objectives This study aimed to assess the clinical and histopathological effects of maximal available and supramaximal energy exposure in direct selective laser trabeculoplasty (DSLT®) on target and nontarget ocular tissues compared with selective laser trabeculoplasty (SLT) and sham treatments.
Liat Mendel Veig +4 more
wiley +1 more source
Blocking Extracellular Cyclophilin A‐Mediated Adhesion Protects Against Bacterial Infection
eCypA promotes bacterial infection by upregulating TGF‐β signaling‐dependent adhesion receptor expression. Pathogens such as IAV, GAS, S. P., and K. P. induce eCypA secretion. Binding of eCypA with TβR2 enhances the affinity of TGF‐β1 and TβR2, which positively regulates adhesion receptors expression via the TGF‐β/Smad signaling pathway, thereby ...
Xiaoyuan Bai +16 more
wiley +1 more source
Mechanistic Evaluation of Luteolin in Wound Healing of Diabetic Foot Ulcer via Nrf2 Signaling
Proposed mechanism by which Luteolin (LU) promotes diabetic foot ulcer healing. LU attenuates hyperglycemia‐induced oxidative stress and lipid peroxidation, improves endothelial cell viability, and suppresses ferroptosis through Nrf2‐dependent antioxidant signaling, thereby accelerating angiogenesis and wound repair. ABSTRACT Diabetic foot ulcers (DFUs)
Muhammed Yusuf +2 more
wiley +1 more source
Increased virulence of rabbit haemorrhagic disease virus associated with genetic resistance in wild Australian rabbits (Oryctolagus cuniculus). [PDF]
Elsworth P +5 more
europepmc +1 more source
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley +1 more source
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó +14 more
wiley +1 more source
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun +10 more
wiley +1 more source

