Results 1 to 10 of about 161,155 (272)

Immune cell pathology in rabbit hemorrhagic disease. [PDF]

Vet World, 2019
Aim: The aim of this research was to study the effect of rabbit hemorrhagic disease virus (RHDV) on the host immune response by examining the cellular composition/pathology of lymphoid organs and serum levels of tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ).
Semerjyan AB, Sargsyan MA, Arzumanyan HH, Hakobyan LH, Abroyan LO, Semerjyan ZB, Avetisyan AS, Karalova EM, Manukyan DM, Matevosyan HS, Krasnikov NF, Karalyan ZA.   +11 more
europepmc   +6 more sources

Immunological effects of ractopamine in rabbits receiving the viral inactivated rabbit hemorrhagic disease vaccine. [PDF]

Open Vet J
Background: There is an obvious lack of information about the effects of ractopamine, a ß-adrenergic agonist, on the growth performance and immune responses of rabbits, particularly in those receiving the viral rabbit hemorrhagic disease (RHD) vaccine.
Shams GA, Ibrahim HA, Hassan HM, Semary NS, Hassan AFI.   +4 more
europepmc   +5 more sources

Structural Basis for Rabbit Hemorrhagic Disease Virus Antibody Specificity. [PDF]

J Virol, 2022
Isolated RHDV antibodies have been used for decades to distinguish between antigenic variants, monitor temporal capsid evolution, and examine neutralizing capacities. In this study, we provided the structural basis for an RHDV GI.2 specific diagnostic antibody (2D9) binding and reveal that a small number of amino acid substitutions at the binding site ...
Leuthold MM, Kilic T, Devant JM, Landeta O, Parra F, Dalton KP, Hansman GS.   +6 more
europepmc   +4 more sources

Rabbit hemorrhagic disease virus type 2 epidemic in a rabbit colony in Japan. [PDF]

J Vet Med Sci, 2021
Twenty-three of 42 European rabbits (Oryctolagus cuniculus), belonging to the same rabbit colony, died in March 2020 (55% mortality) in Chiba prefecture, Japan. The disease course was extremely acute without indicators of death or hemorrhage. Necropsy revealed liver swelling, discoloration, cloudiness and fragility, and pulmonary edema. Histologically,
Fukui H, Shimoda H, Kadekaru S, Henmi C, Une Y.   +4 more
europepmc   +5 more sources

Hyperlipidemia in Rabbit Hemorrhagic Disease

Experimental Animals, 2008
Clinically healthy rabbits were inoculated with rabbit hemorrhagic disease virus (RHDV) and the kinetics of their serum lipid parameters and liver enzymes were monitored. After RHDV inoculation, hyperlipidemia was observed (P(triglyceride)
Sheng-Yi Chen, Jui-Hung Shien, Hong-Kean Ooi   +2 more
openaire   +5 more sources

An outbreak of rabbit hemorrhagic disease (RHD) caused by Lagovirus europaeus GI.2/rabbit hemorrhagic disease virus 2 (RHDV2) in Ehime, Japan. [PDF]

J Vet Med Sci, 2021
A total of ten 1-2-year-old rabbits died within 2 weeks at a facility in Ehime prefecture in May 2019. Necropsy revealed liver discoloration and fragility, hemorrhage of some organs and blood coagulation failure. On histopathologic examination, necrotizing hepatitis was a common finding, together with fibrin thrombi in the small vessels and hemorrhage ...
Katayama A, Miyazaki A, Okazaki N, Nakayama T, Mikami O.   +4 more
europepmc   +5 more sources

Processing of rabbit hemorrhagic disease virus polyprotein [PDF]

Journal of Virology, 1996
Expression of rabbit hemorrhagic disease virus (RHDV) cDNAs in vitro with rabbit reticulocyte lysates and in Escherichia coli have been used to study the proteolytic processing of RHDV polyprotein encoded by ORF1. An epitope tag was used for monitoring the gene products by a specific antibody. We have identified four gene products with molecular masses
José Antonio Boga, Francisco Parra, Rosa Casais, J.M. Martín Alonso   +3 more
openaire   +3 more sources

Origin and Phylodynamics of Rabbit Hemorrhagic Disease Virus [PDF]

Journal of Virology, 2009
ABSTRACT To determine the origin, phylogenetic relationships, and evolutionary dynamics of rabbit hemorrhagic disease virus (RHDV), we examined 210 partial and complete capsid gene nucleotide sequences. Using a Bayesian Markov chain Monte Carlo approach, we estimated that these sequences evolved at a rate of 3.9 × 10 −
Edward C. Holmes, Edward C. Holmes, Andrew Kitchen, Peter J. Kerr   +3 more
openaire   +3 more sources

Identification and characterization of the virus causing rabbit hemorrhagic disease [PDF]

Journal of Virology, 1990
Liver tissue from animals that died of rabbit hemorrhagic disease (RHD) was used to identify the causative agent. After extraction of liver homogenates and sucrose density gradient ultracentrifugation, distinct bands were obtained. The respective gradient fractions reacted positively in an enzyme-linked immunosorbent assay as well as in ...
Frank Weiland, Gregor Meyers, H.-J. Thiel, V F Ohlinger, Bernd Haas   +4 more
openaire   +3 more sources

Pathomorphological characteristics of viral hemorrhagic disease of rabbits

Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies, 2020
The dead animals have a pathomorphological picture with a brightly expressed hemorrhagic diathesis, in many organs there is venous stasis. Blood does not clot for several hours, and at autopsy of organs (heart, lungs, liver, kidneys) it is poured in significant amounts into the body cavity.
Z. V. Khomenko, T. F. Kot, S. V. Guralska, L. V. Bezdіtko, S. S. Zaika   +4 more
openaire   +3 more sources