Rabbit Hemorrhagic Disease (RHD) is a rapidly lethal infectious viral disease of the European Rabbit (Oryctolagus cuniculus) characterized by high mortality rates, acute hepatic necrosis, and disseminated intravascular coagulation. Although this disease is considered enzootic in Europe and parts of Asia, it is rarely seen in the Western Hemisphere ...
exaly +2 more sources
Immunological Cross-Protection between Different Rabbit Hemorrhagic Disease Viruses—Implications for Rabbit Biocontrol and Vaccine Development [PDF]
The use of rabbit hemorrhagic disease virus (RHDV) as a biocontrol agent to control feral rabbit populations in Australia, in combination with circulating endemic strains, provides a unique environment to observe the interactions between different ...
Tiffany W. O’Connor +4 more
doaj +2 more sources
Potent Protease Inhibitors of Highly Pathogenic Lagoviruses: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus [PDF]
Rabbit hemorrhagic disease (RHD) and European brown hare syndrome (EBHS) are highly contagious diseases caused by lagoviruses in the Caliciviridae family.
Krishani Dinali Perera +5 more
doaj +2 more sources
Vaccination against Rabbit Hemorrhagic Disease Virus 2 (RHDV2) Using a Baculovirus Recombinant Vaccine Provides Durable Immunity in Rabbits [PDF]
Rabbit hemorrhagic disease virus 2 (RHDV2) emerged in the United States in 2018 and has spread in both domestic and wild rabbits nationwide. The virus has a high mortality rate and can spread rapidly once introduced in a rabbit population.
Angela M. Bosco-Lauth +10 more
doaj +2 more sources
Emerging Rabbit Hemorrhagic Disease Virus 2 (RHDVb), Australia
To the Editor: In May 2015 an isolate of the recently emerged variant of rabbit hemorrhagic disease virus (RHDV), RHDV2, was identified in an Australian wild rabbit (Oryctolagus cuniculus). RHDV2 (also called RHDVb) was first described in outbreaks in France in 2010 (1), then Italy and Spain in 2011 (2,3) and in Portugal from 2012 onwards (4).
Robyn N. Hall +5 more
doaj +3 more sources
A Brief Update on Rabbit Hemorrhagic Disease Virus [PDF]
Lorenzo Capucci, Antonio Lavazza
doaj +2 more sources
Rabbit hemorrhagic disease virus 2, 2010-2023: a review of global detections and affected species. [PDF]
Asin J +6 more
europepmc +2 more sources
Detection of rabbit hemorrhagic disease virus 2 in formalin-fixed, paraffin-embedded tissues via in situ hybridization. [PDF]
O'Toole AD +3 more
europepmc +2 more sources
Processing of rabbit hemorrhagic disease virus polyprotein [PDF]
Expression of rabbit hemorrhagic disease virus (RHDV) cDNAs in vitro with rabbit reticulocyte lysates and in Escherichia coli have been used to study the proteolytic processing of RHDV polyprotein encoded by ORF1. An epitope tag was used for monitoring the gene products by a specific antibody. We have identified four gene products with molecular masses
J M, Martín Alonso +3 more
openaire +2 more sources
Origin and Phylodynamics of Rabbit Hemorrhagic Disease Virus [PDF]
ABSTRACT To determine the origin, phylogenetic relationships, and evolutionary dynamics of rabbit hemorrhagic disease virus (RHDV), we examined 210 partial and complete capsid gene nucleotide sequences. Using a Bayesian Markov chain Monte Carlo approach, we estimated that these sequences evolved at a rate of 3.9 × 10 −
Peter J, Kerr +2 more
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