Results 101 to 110 of about 24,834 (201)
Aging Cell, EarlyView.MAPT accumulation inhibited CHMP4B expression and thus disrupted ESCRT‐III‐mediated autophagosome‐lysosome fusion, which induced a vicious cycle between MAPT aggregation and autophagic deficits. Aerobic exercise could effectively block the vicious cycle and reverse autophagic deficits by promoting the β2‐AR‐RXRα‐CHMP4B‐ESCRT‐III pathway, reducing ...
Shu‐Guang Bi +12 more
wiley +1 more source
British Journal of Haematology, EarlyView.We report the UK experience of autologous haematopoietic stem cell transplantation (AHSCT) for multiple sclerosis (MS) in 364 patients. In our observational study, transplant‐related mortality was 1.4%, Epstein–Barr virus reactivation occurred in 75.9%, while disability progression‐free survival was 83.5% at 2 years post‐AHSCT and 62.4% at 5 years.
Majid Kazmi +18 more
wiley +1 more source
Cell Proliferation, EarlyView.Our study elucidates the cellular and molecular mechanisms underlying KYNA's protective effects against HIRI. It emphasises that KYNA modulates the methylation status of the Hippo signalling pathway through the activation of AHR, thereby mitigating damage by promoting LATS1 degradation and facilitating the nuclear translocation of YAP. ABSTRACT Hepatic
Wenjie Zheng +10 more
wiley +1 more source
Managing Haemophilic Arthropathy in People With Haemophilia in Japan: An Informal Consensus
Haemophilia, EarlyView.ABSTRACT Introduction People with haemophilia who develop haemophilic arthropathy experience disabling physical effects, limiting functionality and quality of life (QOL). Although Clinical Practice Guidelines are available for haemophilia management, consensus on haemophilic arthropathy management is needed.
Kumiko Ono +13 more
wiley +1 more source
BMC Veterinary Research, 2018 Background Prior to 2010, the lagoviruses that cause rabbit hemorrhagic disease (RHD) in European rabbits (Oryctolagus cuniculus) and European brown hare syndrome (EBHS) in hares (Lepus spp.) were generally genus-specific.
Aleksija S. Neimanis +7 more
doaj +1 more source
Neuroimmune pathophysiology of long COVID
Psychiatry and Clinical Neurosciences, EarlyView.Although COVID‐19 was originally considered a respiratory illness, it is now well established that SARS‐CoV‐2 infection can have far‐reaching impacts on the nervous system. Neurological symptoms such as chemosensory dysfunction are frequently observed during acute infection and approximately 10% of COVID‐19 cases will go on to develop new or persistent
Janna K. Moen +2 more
wiley +1 more source
Veterinary Dermatology, EarlyView.Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis +9 more
wiley +1 more source
Journal of Veterinary Medical Science, 2009 Nine isolates of rabbit hemorrhagic disease virus (RHDV) were used for the genetic characterization of RHDV strains collected from rabbits in Korea between 2006 and 2008. A phylogenetic analysis of the complete VP60 region was performed and the sequences were divided mainly into two groups.
Kyoung-Ki Lee +7 more
openaire +4 more sources
Techniques for subretinal injections in animals
Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley +1 more source
Rapid detection of three rabbit pathogens by use of the Luminex x-TAG assay
BMC Veterinary Research, 2018 Background Domestic rabbits especially New Zealand white rabbits play an important role in biological research. The disease surveillance and quality control are essential to guarantee the results of animal experiments performed on rabbits.
Miaoli Wu +10 more
doaj +1 more source