Results 121 to 130 of about 37,546 (244)

Mouse Vocal Fold Permeability In Vivo: Effects of Novel Low‐Tech Injury and Instillation Methods

The Laryngoscope, EarlyView.
Improving experimental mouse vocal fold injury and instillation approaches is necessary to advance preclinical models of laryngeal disease. We have successfully repurposed low‐tech, quick, and reliable injury and instillation methods established in respiratory research. Using these methods, we show that murine vocal fold epithelium is inherently highly
Renee E. King, Ella T. Ward‐Shaw, Paul F. Lambert   +2 more
wiley   +1 more source

Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]

, 2017
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin, Elliott, Richard M., Rezelj, Veronica V.   +2 more
core   +1 more source

Detecting and attributing climate change effects on vegetation: Australia as a test case

PLANTS, PEOPLE, PLANET, EarlyView.
Climate change is contributing to vegetation changes that threaten life support systems. Yet, inherent climatic variability and past and present human actions—such as clearing, burning and grazing regimes—also alter vegetation and complicate understanding of vegetation change. Australian ecosystems exemplify such complexity.
Laura J. Williams, Rachael V. Gallagher, Sami W. Rifai, Matthew A. Adeleye, Patrick J. Baker, David M. J. S. Bowman, Jake Eckersley, Jacqueline R. England, Michael‐Shawn Fletcher, Pauline F. Grierson, Assaf Inbar, Jürgen Knauer, Clare M. Stephens, Raphaël Trouvé, Belinda E. Medlyn   +14 more
wiley   +1 more source

Peptide Bbeta(15-42) preserves endothelial barrier function in shock [PDF]

, 2009
Loss of vascular barrier function causes leak of fluid and proteins into tissues, extensive leak leads to shock and death. Barriers are largely formed by endothelial cell-cell contacts built up by VE-cadherin and are under the control of RhoGTPases. Here
Atrasheuskaya, Alena, Bukin, Eugenij, Friedl, Peter, Gröger, Marion, Hofer-Warbinek, Renate, Ignatyev, George, Knapp, Sylvia, Matt, Ulrich, Pasteiner, Waltraud, Petzelbauer, Peter, Reingruber, Sonja, Zacharowski, Kai, Zinkl, Daniela   +12 more
core  

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

Rare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu, Shao‐Sheng Jia, Rong‐Bang Sun, Tong Zhang, Ling‐Chuang Bai, Di Mei, Shi‐Jie Zhu, Lan Chen, Shao‐Kang Guan   +8 more
wiley   +1 more source

Inhibition of interferon signaling improves rabbit calicivirus replication in biliary organoid cultures

Journal of Virology
The Rabbit hemorrhagic disease virus (RHDV) was discovered 40 years ago. This highly pathogenic virus threatens the integrity of ecosystems in the European rabbit’s native range, while in Australia, it is used as a biocontrol tool to manage overabundant ...
Elena Smertina, Megan Pavy, Nias Y. G. Peng, Omid Fahri, Maria Jenckel, Tanja Strive, Michael Frese, Ina L. Smith   +7 more
doaj   +1 more source

Therapeutic Efficacy of the Supersulfide Donor NAC‐S2 in Influenza Virus Pneumonia via Suppression of Excessive Inflammatory Responses

Microbiology and Immunology, EarlyView.
ABSTRACT Influenza pneumonia is characterized by excessive inflammatory responses that contribute to severe lung injury and mortality. Supersulfides, endogenously produced cysteine‐derived persulfides and polysulfides, exert potent antioxidant, anti‐ferroptotic, and anti‐inflammatory activities; however, their therapeutic potential after disease onset ...
Foysal Hossen, Takahisa Kouwaki, Yukio Fujiwara, Hiroyasu Tsutsuki, Tianli Zhang, Chunyu Guo, Azizur Rahman, Yoshihiro Komohara, Hiroyuki Oshiumi, Tomohiro Sawa   +9 more
wiley   +1 more source

First Description and Characterisation of Lactococcus garvieae Strains Causing Septicaemic Disease in Farmed Sea Bass (Dicentrarchus labrax; Linnaeus) in Spain

Journal of Fish Diseases, EarlyView.
ABSTRACT This study presents the first description and characterisation of Lactococcus garvieae isolated from diseased European sea bass (Dicentrarchus labrax) farmed in Spain. During autumn 2023, two fish farms were affected by infectious outbreaks causing moderate cumulative fish mortality (5%–10%). Diseased fish showed clinical signs of haemorrhagic
Belén Fouz, Evelyn Carballeda‐Carrasco, Javier Barriga‐Cuartero, Yolanda Torres‐Corral, Álvaro Robles, Carlos Zarza, Ysabel Santos   +6 more
wiley   +1 more source

Comparative Phylodynamics of Rabbit Hemorrhagic Disease Virus in Australia and New Zealand [PDF]

Journal of Virology, 2015
ABSTRACTThe introduction of rabbit hemorrhagic disease virus (RHDV) into Australia and New Zealand during the 1990s as a means of controlling feral rabbits is an important case study in viral emergence. Both epidemics are exceptional in that the founder viruses share an origin and the timing of their release is known, providing a unique opportunity to ...
John-Sebastian, Eden, John, Kovaliski, Janine A, Duckworth, Grace, Swain, Jackie E, Mahar, Tanja, Strive, Edward C, Holmes   +6 more
openaire   +2 more sources

Investigation of the global transportation of Culicoides biting midges, vectors of livestock and equid arboviruses, from flower‐packing plants in Kenya

Medical and Veterinary Entomology, EarlyView.
Arboviral diseases spread by Culicoides biting midges have been introduced into Europe by unknown means. A possible route is the carriage of midges with cut flowers shipped to flower markets. We sampled Culicoides in and around a cut flower farm in Kenya; midges were caught in the vicinity and a greenhouse, but not where flowers are processed.
Jessica Eleanor Stokes, Karien Labuschagne, Eric Maurice Fèvre, Matthew Baylis   +3 more
wiley   +1 more source