Results 61 to 70 of about 24,359 (148)

Recombinant Lactobacillus casei Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits. [PDF]

Vaccines (Basel), 2019
Rabbit hemorrhagic disease virus (RHDV) is the causative agent of rabbit hemorrhagic disease (RHD). RHD, characterized by hemorrhaging, liver necrosis, and high morbidity and mortality in rabbits and hares, causes severe economic losses in the rabbit ...
Wang L, Xia T, Guo T, Ru Y, Jiang Y, Cui W, Zhou H, Qiao X, Tang L, Xu Y, Li Y.   +10 more
europepmc   +2 more sources

Immunological Cross-Protection between Different Rabbit Hemorrhagic Disease Viruses—Implications for Rabbit Biocontrol and Vaccine Development

Vaccines, 2022
The use of rabbit hemorrhagic disease virus (RHDV) as a biocontrol agent to control feral rabbit populations in Australia, in combination with circulating endemic strains, provides a unique environment to observe the interactions between different ...
Tiffany W. O’Connor, Andrew J. Read, Robyn N. Hall, Tanja Strive, Peter D. Kirkland   +4 more
doaj   +1 more source

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai, Yongxia Li, Jiarui Du, Gang Shen, Meimei Fan, Zuopeng Su, Fulin Xu, Fang Yuan   +7 more
wiley   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Immunogenicity and Efficacy of a Bivalent Inactivated Vaccine against Rabbit Hemorrhagic Disease Virus

World's Veterinary Journal, 2022
Rabbit hemorrhagic disease is a fatal threat to rabbits that causes sustainability problems and substantial economic losses. The aim of the current study was to compare the immuno-enhancing effects of a bivalent inactivated rabbit hemorrhagic disease ...
S. Abodalal, M. A. Abdrabo, L. Omar
semanticscholar   +1 more source

Characteristics of a new variant of rabbit haemorrhagic disease virus – RHDV2

Acta Biologica, 2019
RHD (Rabbit Haemorrhagic Disease) is an etiologic agent that causes viral haemorrhagic disease of rabbits, which is also referred to as rabbit plague. The desire to explore knowledge about this pathogen in the world results not only from its similarity ...
Dominika Bębnowska, Paulina Niedźwiedzka-Rystwej   +1 more
doaj   +1 more source

Dynamics of Humoral Immunity to Myxoma and Rabbit Hemorrhagic Disease Viruses in Wild European Rabbits Assessed by Longitudinal Semiquantitative Serology

Microbiology Spectrum, 2023
Myxoma virus (MYXV) and rabbit hemorrhagic disease virus (RHDV) are important drivers of the population decline of the European rabbit, an endangered keystone species.
Joana Coelho, Henrique Pacheco, Marta Rafael, Saúl Jiménez-Ruiz, Paulo Célio Alves, Nuno Santos   +5 more
doaj   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Negative trends in Rabbit populations in ‘Pest’ and ‘Non-Pest’ areas of central Spain after the outbreak of rabbit hemorrhagic disease virus 2

Zeitschrift f\ ur Jagdwissenschaft
Despite increased conservation efforts, the European rabbit (Oryctolagus cuniculus), a keystone species in the Iberian Peninsula, continues declining due to habitat degradation and viral diseases. Following the 2011 outbreak of Rabbit Hemorrhagic Disease
Cristina Marin-Sáez, M. Delibes‐Mateos, Brian Cooke, Simone Santoro, F. Castro, R. Villafuerte   +5 more
semanticscholar   +1 more source

Bioinformatics analysis of capsid protein of different subtypes rabbit hemorrhagic disease virus. [PDF]

BMC Vet Res, 2019
Background Rabbit Hemorrhagic Disease Virus (RHDV) belongs to the Caliciviridae family, is a highly lethal pathogen to rabbits. Increasing numbers of studies have demonstrated the existence of antigenic variation in RHDV, leading to the emergence of a ...
Qi R, Zhu J, Miao Q, Tang A, Dong D, Wang X, Liu G.   +6 more
europepmc   +2 more sources