Results 51 to 60 of about 957 (133)

Immunogenicity of Multi-Target Chimeric RHDV Virus-Like Particles Delivering Foreign B-Cell Epitopes

open access: yesVaccines, 2022
The rabbit hemorrhagic disease virus (RHDV) vaccine platform is a nanoparticle composed of 180 copies of the viral capsid protein, VP60, self-assembled into virus-like particles (VLPs).
María Zamora-Ceballos   +5 more
doaj   +1 more source

Facts about Wildlife Diseases: Rabbit Hemorrhagic Disease Virus Serotype 2 (RHDV2)

open access: yesEDIS, 2022
This publication provides information on rabbit hemorrhagic disease virus serotype 2 (RHDV2) and discusses infection, clinical signs, treatment, prevention, and reporting. Written by Catherine E. Dixon and Juan M.
Catherine E. Dixon   +1 more
doaj   +3 more sources

Multiple global‐change drivers and cascading effects in Mediterranean ecosystems: Lessons from an iconic national park

open access: yesConservation Science and Practice, Volume 8, Issue 6, June 2026.
Mediterranean ecosystems face complex, multi‐trophic impacts from global‐change drivers, yet responses are often studied in isolation. Using the Doñana Protected Area as a case study, we illustrate how anthropogenic pressures on key species like cork oaks and rabbits, as well as increases in species like wild boar and invasive crayfish, lead to ...
Maria Paniw   +23 more
wiley   +1 more source

Remote sensing reveals that wild herbivores limit senescent vegetation accumulation on dryland conservation reserves

open access: yesEcological Applications, Volume 36, Issue 3, April 2026.
Abstract Wild herbivores threaten vegetation recovery on dryland conservation reserves globally. Monitoring herbivore impacts in remote drylands is difficult because vegetation biomass transitions between living and senescent states in response to irregular precipitation events.
Matt S. Smith   +3 more
wiley   +1 more source

Fungal Panzootic Increasingly Threatens Temperate Amphibian Species While Impact Has Stabilised in Equatorial Regions

open access: yesGlobal Change Biology, Volume 32, Issue 1, January 2026.
The worldwide erosion of amphibian biodiversity has been linked to the fungal pathogen Batrachochytrium dendrobatidis (Bd). Our study reveals that with increased frequency of testing across time periods, the proportion of Bd‐positive species worsening in IUCN Red List category is increasing in temperate regions, but not around equatorial areas.
Luke E. B. Goodyear   +4 more
wiley   +1 more source

Nucleolin mediates the internalization of rabbit hemorrhagic disease virus through clathrin-dependent endocytosis.

open access: yesPLoS Pathogens, 2018
Rabbit hemorrhagic disease virus (RHDV) is an important member of the Caliciviridae family and a highly lethal pathogen in rabbits. Although the cell receptor of RHDV has been identified, the mechanism underlying RHDV internalization remains unknown.
Jie Zhu   +8 more
doaj   +1 more source

Enhancing Rabbit Welfare in Intensive Production Systems: A Review

open access: yesThe Scientific World Journal, Volume 2026, Issue 1, 2026.
Rabbit farming is an important sector of animal husbandry worldwide, providing meat, fur, and research models. However, intensive production systems often compromise the welfare of rabbits by restricting their natural behaviors and exposing them to physical and psychological stressors.
Iryna Lastovska   +8 more
wiley   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

Advancing ORFV‐Based Therapeutics to the Clinical Stage

open access: yesReviews in Medical Virology, Volume 35, Issue 3, May 2025.
ABSTRACT The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses without inducing significant anti‐vector immunity.
Matthias Helmold, Ralf Amann
wiley   +1 more source

Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39

open access: yesBritish Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier   +4 more
wiley   +1 more source

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