Results 51 to 60 of about 968 (131)

Multiple Introductions of Rabbit Hemorrhagic Disease Virus Lagovirus europaeus/GI.2 in Africa

Biology, 2021
Rabbit hemorrhagic disease (RHD) causes high mortality and morbidity in European rabbits (Oryctolagus cuniculus). In Africa, the presence of the causative agent, the rabbit hemorrhagic disease virus (RHDV), was first confirmed in 1992 (genotype Lagovirus
Faten Ben Chehida, Ana M. Lopes, João V. Côrte-Real, Soufien Sghaier, Rim Aouini, Lilia Messadi, Joana Abrantes   +6 more
doaj   +1 more source

Rabbit hemorrhagic disease virus VP60 protein expressed in recombinant swinepox virus self-assembles into virus-like particles with strong immunogenicity in rabbits

Frontiers in Microbiology, 2022
Rabbit Hemorrhagic Disease (RHD) is an economically significant infectious disease of rabbits, and its infection causes severe losses in the meat and fur industry.
Changjin Liu, Min Lin, Huanyi Hu, Xiaolan Liu, Yanchao Bian, Xiaohua Huang, Xiaoxiang Li, Wenyang Yu, Feng Luo, Shunzhou Deng   +9 more
doaj   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4619-4639, July 2026.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

Multiple global‐change drivers and cascading effects in Mediterranean ecosystems: Lessons from an iconic national park

Conservation Science and Practice, Volume 8, Issue 6, June 2026.
Mediterranean ecosystems face complex, multi‐trophic impacts from global‐change drivers, yet responses are often studied in isolation. Using the Doñana Protected Area as a case study, we illustrate how anthropogenic pressures on key species like cork oaks and rabbits, as well as increases in species like wild boar and invasive crayfish, lead to ...
Maria Paniw, Duarte S. Viana, Cristina Coccia, Virginia Domínguez‐García, Iñigo Donázar‐Aramendía, Sebastiano de Franciscis, Alberto García‐Rodríguez, Simone Guareschi, Pablo Homet, Jose B. Lanuza, Cosme López‐Calderón, Irene Mendoza, Eva Moracho, Laetitia M. Navarro, Javier Puy, José M. Reyes‐González, María José Ruiz‐López, Zulima Tablado, Elena Tena, Estefanía Tobajas, Elena Velado‐Alonso, Pablo Villalva, Nacho Villar, Marcello D'Amico   +23 more
wiley   +1 more source

Remote sensing reveals that wild herbivores limit senescent vegetation accumulation on dryland conservation reserves

Ecological Applications, Volume 36, Issue 3, April 2026.
Abstract Wild herbivores threaten vegetation recovery on dryland conservation reserves globally. Monitoring herbivore impacts in remote drylands is difficult because vegetation biomass transitions between living and senescent states in response to irregular precipitation events.
Matt S. Smith, Adrian G. Fisher, Graeme Finlayson, Mike Letnic   +3 more
wiley   +1 more source

Fungal Panzootic Increasingly Threatens Temperate Amphibian Species While Impact Has Stabilised in Equatorial Regions

Global Change Biology, Volume 32, Issue 1, January 2026.
The worldwide erosion of amphibian biodiversity has been linked to the fungal pathogen Batrachochytrium dendrobatidis (Bd). Our study reveals that with increased frequency of testing across time periods, the proportion of Bd‐positive species worsening in IUCN Red List category is increasing in temperate regions, but not around equatorial areas.
Luke E. B. Goodyear, Deanna H. Olson, Kathryn L. Ronnenberg, Jaime Bosch, Daniel Pincheira‐Donoso   +4 more
wiley   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

Advancing ORFV‐Based Therapeutics to the Clinical Stage

Reviews in Medical Virology, Volume 35, Issue 3, May 2025.
ABSTRACT The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses without inducing significant anti‐vector immunity.
Matthias Helmold, Ralf Amann
wiley   +1 more source

Potent Protease Inhibitors of Highly Pathogenic Lagoviruses: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus

Microbiology Spectrum, 2022
Rabbit hemorrhagic disease (RHD) and European brown hare syndrome (EBHS) are highly contagious diseases caused by lagoviruses in the Caliciviridae family.
Krishani Dinali Perera, David Johnson, Scott Lovell, William C. Groutas, Kyeong-Ok Chang, Yunjeong Kim   +5 more
doaj   +1 more source

Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39

British Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier, Viktoria M. S. Kjær, Stephen Griffin, Birthe B. Kragelund, Mette M. Rosenkilde   +4 more
wiley   +1 more source