Results 181 to 190 of about 1,222,322 (376)
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
LOCAL IMMUNIZATION OF RABBITS TO CUTANEOUS INFECTION WITH STAPHYLOCOCCUS AUREUS [PDF]
Tracy B. Mallory, Alexander Marble
openalex +1 more source
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
wiley +1 more source
A STUDY OF PLASMA PROTEIN ALTERATIONS IN RABBITS INFECTED WITH TYPE I PNEUMOCOCCI [PDF]
Ralph F. Jacox, Alexandra Feldmahn
openalex +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Microdetermination of nicotine in rabbit urine by BrCN reaction
Iwao Yamamoto+2 more
openalex +2 more sources
Immune Reactions in Rabbits Injected with Micrococci from Acute Poliomyelitis [PDF]
G. Mathers, Kenneth W. Howell
openalex +1 more source
Es una guía práctica para los amantes de animales de compañía que quieran saber cómo cuidar un conejo. Hay mucha información sobre cómo elegirlo, el equipo que va a necesitar y la forma de limpiar su conejera. También hay consejos sobre aseo personal así como los aspectos típicos de su comportamiento.
Patchett, Fiona, Fox, Christyan (il.)
openaire +1 more source
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu+7 more
wiley +1 more source