Results 121 to 130 of about 69,437 (285)
Cell Proliferation, EarlyView.Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin +4 more
wiley +1 more source
How do Viruses Attack Anti-Virus Programs [PDF]
Umakant Mishra, "How do Viruses Attack Anti-virus Programs",
TRIZsite Journal, June 2012,
http://trizsite.tk/trizsite/articles/default.asp?month=Jun&year=2012, 2013 As the anti-viruses run in a trusted kernel level any loophole in the anti-virus program can enable attackers to take full control over the computer system and steal data or do serious damages. Hence the anti-virus engines must be developed with proper security in mind.
arxiv
Understanding the fate of corona virus transmission using a simple model [PDF]
arXiv, 2020 We propose a simple model for understanding the kinetics of corona virus transmission. Our model assume spreading of corona virus can happen from one to another only, if someone without enough protection comes close contact to a person carrying the corona virus.
arxiv
Journal of Biomedical Science, 2012 Background Rabies is known to be lethal in human. Treatment with passive immunity for the rabies is effective only when the patients have not shown the central nerve system (CNS) signs.
Liao Pi-Hung +6 more
doaj +1 more source
Type I interferon signalling and interferon‐responsive microglia in health and disease
The FEBS Journal, EarlyView.Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya +1 more
wiley +1 more source
Epidemics in Multipartite Networks: Emergent Dynamics [PDF]
arXiv, 2013 Single virus epidemics over complete networks are widely explored in the literature as the fraction of infected nodes is, under appropriate microscopic modeling of the virus infection, a Markov process. With non-complete networks, this macroscopic variable is no longer Markov.
arxiv
A small molecule drug candidate targeting SARS-CoV-2 main protease [PDF]
arXiv, 2020 A new coronavirus identified as SARS-CoV-2 virus has brought the world to a state of crisis, causing a major pandemic, claiming more than 433,000 lives and instigating major financial damage to the global economy. Despite current efforts, developing safe and effective treatments remains a major challenge.
arxiv
Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry
The Journal of Physiology, EarlyView.Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley +1 more source
Rabies screen reveals GPe control of cocaine-triggered plasticity. [PDF]
, 2017 Identification of neural circuit changes that contribute to behavioural plasticity has routinely been conducted on candidate circuits that were preselected on the basis of previous results.
AE Stepien +54 more
core +2 more sources
Pandemic Prevention Paradigms: Understanding Global Health Governance
Public Health Challenges, Volume 4, Issue 2, June 2025.One Health is an emerging area of integrative studies and interventions aimed at preventing zoonotic diseases by addressing human, animal, and environmental interactions. A fundamental aspect of the concept is understanding how these interactions influence health outcomes among humans, animals, and ecosystems. Developed initially to respond to the need
Soheil Sadr +10 more
wiley +1 more source