Results 121 to 130 of about 1,739,706 (302)

Incorporation of membrane-anchored flagellin or Escherichia coli heat-labile enterotoxin B subunit enhances the immunogenicity of rabies virus-like particles in mice and dogs

open access: yesFrontiers in Microbiology, 2015
Rabies remains an important worldwide public health threat, so safe, effective, and affordable vaccines are still being sought. Virus-like particle-based vaccines targeting various viral pathogens have been successfully produced, licensed, and ...
Yinglin Qi   +6 more
semanticscholar   +1 more source

Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
Bats are recognized to have distinct immune systems from other vertebrates that may allow them to host virulent pathogens without showing disease. However, these flying mammals are also incredibly diverse, such that bats should not be expected to be immunologically homogenous.
Daniel J. Becker   +11 more
wiley   +1 more source

Protection Against CNS-Targeted Rabies Virus Infection is Dependent upon Type-1 Immune Mechanisms Induced by Live-Attenuated Rabies Vaccines

open access: yesTropical Medicine and Infectious Disease, 2017
Rabies remains a major public health issue worldwide, especially in developing countries where access to medical care can represent a real challenge. While there is still no cure for rabies, it is a vaccine-preventable disease with pre- and post-exposure
Aurore Lebrun   +4 more
doaj   +1 more source

Comparing Rabies Antibody Titres in Imported Dogs to a Population of Dogs in Ontario, Canada

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Introduction Vaccinating dogs against rabies virus is essential for protecting animal and public health. Most dogs imported into Canada must have a valid rabies vaccination certificate but do not require serological testing to confirm response to vaccination.
Catherine R. Belanger   +4 more
wiley   +1 more source

Not all surveillance data are created equal—A multi‐method dynamic occupancy approach to determine rabies elimination from wildlife [PDF]

open access: yes, 2019
1. A necessary component of elimination programmes for wildlife disease is effective surveillance. The ability to distinguish between disease freedom and non‐detection can mean the difference between a successful elimination campaign and new epizootics ...
Cliquet F.   +10 more
core   +2 more sources

Deforestation and Bovine Rabies Outbreaks in Costa Rica, 1985–2020

open access: yesEmerging Infectious Diseases
In Latin America, rabies virus has persisted in a cycle between Desmodus rotundus vampire bats and cattle, potentially enhanced by deforestation. We modeled bovine rabies virus outbreaks in Costa Rica relative to land-use indicators and found spatial ...
Christie Jones   +3 more
doaj   +1 more source

The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans, in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs   +6 more
wiley   +1 more source

Successful strategies implemented towards the elimination of canine rabies in the Western Hemisphere [PDF]

open access: yes, 2017
Almost all cases of human rabies result from dog bites, making the elimination of canine rabies a global priority. During recent decades, many countries in the Western Hemisphere have carried out large-scale dog vaccination campaigns, controlled their ...
Damon, Inger   +9 more
core   +1 more source

Sufficient virus-neutralizing antibody in the central nerve system improves the survival of rabid rats

open access: yesJournal of Biomedical Science, 2012
Background Rabies is known to be lethal in human. Treatment with passive immunity for the rabies is effective only when the patients have not shown the central nerve system (CNS) signs.
Liao Pi-Hung   +6 more
doaj   +1 more source

Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons

open access: yesNature Protocols, 2010
Recombinant rabies viruses rendered replication-deficient by the deletion of their envelope glycoprotein gene are useful tools for neuroscientists, permitting (1) extraordinarily high transgene expression levels within neurons, (2) retrograde infection ...
Citation Wickersham   +3 more
semanticscholar   +1 more source

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