Results 101 to 110 of about 1,084,357 (231)

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen, Jiayi Wang, Jimin Yu, Yiran Zhou, Lihai Liu, Jing Liu, Liang Wang   +6 more
wiley   +1 more source

Transient expression of the rabies glycoprotein in soybean [PDF]

, 2021
Rabies is a highly preventable disease that is still claiming thousands of lives every year. An edible rabies vaccine for animals would reduce the cost and resources needed for the vaccine to reach less developed regions by simplifying administration of ...
NC DOCKS at Western Carolina University, Williams, Grayson   +1 more
core  

Bioengineered Extracellular Vesicles Mitigate Neuroinflammation by Neutralizing Pneumolysin and Delaying Disease Onset in Experimental Pneumococcal Meningitis

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Bacterial meningitis is a life‐threatening neurological disorder frequently caused by a Streptococcus pneumoniae (the pneumococcus) infection of the brain. Standard treatment consists of antibiotics to eliminate bacteria and dexamethasone to reduce inflammation.
Kristine Farmen, Doste R. Mamand, Miguel Tofiño‐Vian, Georgia Yfanti, Xiuming Liang, Houze Zhou, Vicky W. Q. Hou, Samir El Andaloussi, Oscar P. B. Wiklander, Federico Iovino   +9 more
wiley   +1 more source

Domestic dog demographic structure and dynamics relevant to rabies control planning in urban areas in Africa: the case of Iringa, Tanzania [PDF]

, 2012
<p>Background Mass vaccinations of domestic dogs have been shown to effectively control canine rabies and hence human exposure to rabies. Knowledge of dog population demography is essential for planning effective rabies vaccination programmes ...
Kazwala Rudovick R, Kazwala, R. R., Penelope Vounatsou, Kazwala, Rudovick R., Vounatsou Penelope, Gsell, A.S., Kazwala, R.R., Zinsstag Jakob, Vounatsou, P., Knobel Darryn L, Cleaveland, S., Darryn L Knobel, Alena S Gsell, Kazwala, R. R., Gsell, A. S., Gsell, Alena S., Zinsstag, Jakob, Knobel, D.L., Gsell Alena S, Knobel, D. L., Rudovick R Kazwala, Jakob Zinsstag, Knobel, Darryn Leslie, Vounatsou, Penelope, Zinsstag, J.   +24 more
core   +3 more sources

Short-interfering RNAs as antivirals against rabies

Brazilian Journal of Infectious Diseases
This study aimed to test in vitro a RNA-interference based antiviral approach for rabies with short-interfering RNAs (siRNAs) against rabies virus nucleoprotein mRNA.
Paulo Eduardo Brandão, Juliana Galera Castilho, Willian Fahl, Pedro Carnieli Jr., Rafael de Novaes Oliveira, Carla Isabel Macedo, Maria Luiza Carrieri, Ivanete Kotait   +7 more
doaj   +1 more source

Qualitative Assessment of One Health Operationalization at the Central Level and in Two Border Districts of Sierra Leone

Public Health Challenges, Volume 5, Issue 3, September 2026.
Implementation of the One Health approach in Sierra Leone was stronger at the central level than in districts and communities, where coordination, surveillance, workforce capacity, and funding were limited. Strengthening integrated systems and dedicated financing is essential for effective prevention and control of zoonotic disease threats.
Joseph Anderson Bunting‐Graden, Fatmata Sawaneh, Alhassan Mayei, Monya Konneh, Patrick Fatoma, Emmanuel Komba Finoh, Lily Kainwo, Wesen Konteh, Mukeh Kenneth Fahnbulleh, Klaere Heyden, Mohamed Alex Vandi, Foday Sahr, Adel Hussein Elduma Abdalla, Rashid Ansumana, Kinley Wangdi, Philip P. Mshelbwala   +15 more
wiley   +1 more source

A Study on the Ocular Infection with Rabies Virus in Mouse

Journal of Medical Microbiology and Infectious Diseases, 2014
Introduction: The most common mode of rabies virus transmission is through a bite wound or contact of broken skin with saliva of a rabid animal. Various other routes of virus transmission include exposure of mucous membranes (i.e.
Atefeh Pilehvar Zavareh, Mohammadreza Mahzounieh, Mohammadreza Shirzadi, Rouzbeh Bashar, Alireza Zavareh, Nader Howaizi, Firuzeh Farahtaj, Alireza Janani, Alireza Gholami   +8 more
doaj  

Oligosaccharides of the glycoprotein of rabies virus [PDF]

Journal of Virology, 1977
The number of oligosaccharide side chains on rabies virus glycoprotein (G-protein) was investigated. Analysis of glycopeptides obtained by protease digestion of desialated G-protein revealed three discrete glycopeptides. Comparison of the protease digestion products from desialated and from untreated G-protein indicated a heterogeneity among the ...
openaire   +2 more sources

Seroprevalence of Lumpy Skin Disease and Livestock Owners’ Knowledge, Attitudes and Practices in Selected Districts of Kazakhstan

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
A cross‐sectional study conducted in 12 districts across four regions of Kazakhstan assessed LSDV seropositivity in cattle and livestock owners’ knowledge, attitudes and practices. Serum samples from 338 cattle were tested by ELISA, and questionnaires were completed by 533 livestock owners. Animal‐level and herd‐level seroprevalence were 23.4% and 18.8%
Assylay Sarzhigitova, Lespek Kutumbetov, Kuandyk Zhugunissov, Raikhan Nissanova, Nazerke Kemalova, Aigul Kaliyeva, Sarsenbay Abdrakhmanov, Yerzhan Ospanov, Nadezhda Burambayeva, Arman Issimov, Gulmira Abulgazimova, Leila Kassymbekova   +11 more
wiley   +1 more source

Protective efficacy of combined monoclonal antibody docaravimab and miromavimab preparation against classical rabies virus: A preclinical study in BALB/c mice

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Medicinal products based on monoclonal antibodies (mAbs) is one of the promising options for post-exposure rabies prophylaxis. Since Russian pharmaceutical market does not offer anti-rabies mAbs, a combined docaravimab and miromavimab ...
S. V. Borisevich, V. V. Rubtsov, M. N. Pistsov, S. Ya. Loginova, V. T. Krotkov, R. V. Sakharov, D. A. Kuznetsov, T. E. Sizikova, S. V. Savenko, K. I. Yanovskaya, A. V. Ovchinnikov, A. N. Mironov   +11 more
doaj   +1 more source