Results 11 to 20 of about 1,739,706 (302)
Presence of virus neutralizing antibodies in cerebral spinal fluid correlates with non-lethal rabies in dogs. [PDF]
PLoS Neglected Tropical Diseases, 2013 Rabies is traditionally considered a uniformly fatal disease after onset of clinical manifestations. However, increasing evidence indicates that non-lethal infection as well as recovery from flaccid paralysis and encephalitis occurs in laboratory animals
Clement W Gnanadurai +12 more
doaj +5 more sources
Antigenic characterisation of lyssaviruses in South Africa [PDF]
Onderstepoort Journal of Veterinary Research, 2014 There are at least six Lyssavirus species that have been isolated in Africa, which include classical rabies virus, Lagos bat virus, Mokola virus, Duvenhage virus, Shimoni bat virus and Ikoma lyssavirus.
Ernest Ngoepe +3 more
doaj +2 more sources
Elucidating the phylodynamics of endemic rabies virus in eastern Africa using whole-genome sequencing [PDF]
Virus Evolution, 2015 Many of the pathogens perceived to pose the greatest risk to humans are viral zoonoses, responsible for a range of emerging and endemic infectious diseases.
K. Brunker +13 more
semanticscholar +3 more sources
bioRxiv, 2021 Rabies infection is nearly 100% lethal if untreated and kills over 50,000 people annually, many of them children. Existing rabies vaccines target the rabies virus glycoprotein (RABV-G) but generate short-lived immune responses, likely because the protein
H. Callaway +7 more
semanticscholar +1 more source
The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system. [PDF]
PLoS Neglected Tropical Diseases, 2009 The pathogenesis of rabies is associated with the inability to deliver immune effectors across the blood-brain barrier and to clear virulent rabies virus from CNS tissues. However, the mechanisms that facilitate immune effector entry into CNS tissues are
D Craig Hooper +3 more
doaj +1 more source
Expression of Interferon Gamma by a Recombinant Rabies Virus Strongly Attenuates the Pathogenicity of the Virus via Induction of Type I Interferon [PDF]
Journal of Virology, 2014 UNLABELLED: Previous animal model experiments have shown a correlation between interferon gamma (IFN-γ) expression and both survival from infection with attenuated rabies virus (RABV) and reduction of neurological sequelae.
Darryll A. Barkhouse +5 more
semanticscholar +3 more sources
Advances in the progress of monoclonal antibodies for rabies
Human Vaccines & Immunotherapeutics, 2022 Rabies is a highly fatal zoonotic disease caused by the rabies virus invading the central nervous system. When suspected of exposure to the rabies virus, post-exposure prophylaxis should be administered as soon as possible.
Linlin Fan +3 more
doaj +1 more source
The Phylogeography of Rabies in Grenada, West Indies, and Implications for Control [PDF]
, 2014 In Grenada, West Indies, rabies is endemic, and is thought to be maintained in a wildlife host, the small Indian mongoose (Herpestes auropunctatus) with occasional spillover into other hosts.
Adelaide +17 more
core +8 more sources
PLoS Neglected Tropical Diseases, 2020 Rabies has been a widely feared disease for thousands of years, with records of rabid dogs as early as ancient Egyptian and Mesopotamian texts. The reputation of rabies as being inevitably fatal, together with its ability to affect all mammalian species,
Susanna W. Gold +3 more
semanticscholar +1 more source