Results 41 to 50 of about 33,698 (178)

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

open access: yesInterdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang   +13 more
wiley   +1 more source

Structural Proteins of Rabies Virus [PDF]

open access: yesJournal of Virology, 1971
Purified rabies virions, unlabeled or labeled with radioactive amino acids or d -glucosamine, were dissociated into their polypeptides by treatment with sodium dodecyl sulfate in a reducing environment and fractionated by electroiphoresis in sodium dodecyl sulfate-containing polyacrylamide gel. The molecular weights
F, Sokol, D, Stancek, H, Koprowski
openaire   +2 more sources

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang   +5 more
wiley   +1 more source

Impact of general anaesthesia on immune response to first rabies vaccination in seronegative domestic cats

open access: yesVeterinary Record, EarlyView.
Abstract Background Despite common concerns, evidence that anaesthesia impairs vaccine efficacy remains limited. This study assessed the impact of general anaesthesia on the immune response to rabies vaccination in cats. Methods Thirty‐five healthy female cats (6–12 months old) undergoing elective spaying were enrolled.
Pierre Bessière   +8 more
wiley   +1 more source

Rabies virus glycoprotein variants display different patterns in rabies monosynaptic tracing

open access: yesFrontiers in Neuroanatomy, 2014
Rabies virus (RV) has been widely used to trace multi-synaptic neuronal circuits. The recent development of glycoprotein-deficient rabies virus (RV-ΔG) expressing various proteins has enabled analyses of both the structure and function of neuronal ...
Takuma eMori, Kinjiro eMorimoto
doaj   +1 more source

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

open access: yesVeterinary Record, EarlyView.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson   +2 more
wiley   +1 more source

Ecology of declining populations of gray foxes (Urocyon cinereoargenteus) in Indiana, USA Ecología de las poblaciones en declive de zorros grises (Urocyon cinereoargenteus) en Indiana, EE.UU.

open access: yesWildlife Monographs, EarlyView.
We estimated seasonal space use, cover selection, and resource selection; evaluated gene flow and potential genetic barriers; and assessed cause‐specific survival rates and reproduction of radiomarked gray foxes in Indiana, USA. Our results provide evidence that gray foxes in Indiana are an edge species with relatively large home ranges, relatively low
Tim L. Hiller   +5 more
wiley   +1 more source

Abortive vampire bat rabies infections in Peruvian peridomestic livestock.

open access: yesPLoS Neglected Tropical Diseases, 2020
Rabies virus infections normally cause universally lethal encephalitis across mammals. However, 'abortive infections' which are resolved prior to the onset of lethal disease have been described in bats and a variety of non-reservoir species.
Julio A Benavides   +8 more
doaj   +1 more source

Rabies virus antinucleoprotein antibody protects against rabies virus challenge in vivo and inhibits rabies virus replication in vitro [PDF]

open access: yesJournal of Virology, 1993
We previously reported that A/WySnJ mice vaccinated via a tail scratch with a recombinant raccoon poxvirus (RCN) expressing the rabies virus internal structural nucleoprotein (N) (RCN-N) were protected against a street rabies virus (D. L. Lodmell, J. W. Sumner, J.J. Esposito, W.J. Bellini, and L. C. Ewalt, J. Virol. 65:3400-3405, 1991).
D L, Lodmell, J J, Esposito, L C, Ewalt
openaire   +2 more sources

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

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