Results 51 to 60 of about 1,160,275 (227)

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

open access: yesAdvanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan   +8 more
wiley   +1 more source

Antigenic characterisation of lyssaviruses in South Africa

open access: yesOnderstepoort Journal of Veterinary Research, 2014
There are at least six Lyssavirus species that have been isolated in Africa, which include classical rabies virus, Lagos bat virus, Mokola virus, Duvenhage virus, Shimoni bat virus and Ikoma lyssavirus.
Ernest Ngoepe   +3 more
doaj   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

open access: yesAdvanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu   +11 more
wiley   +1 more source

Rabies re-emergence after long-term disease freedom (Amur Oblast, Russia)

open access: yesВетеринария сегодня, 2022
Retrospective descriptive epizootological study was conducted in the Amur Oblast (Russian Far East), where a rabies outbreak was reported in 2018. The aim of the study was to analyze probable routes of rabies introduction and features of its spatial and ...
A. D. Botvinkin   +13 more
doaj   +1 more source

Carrion ecology: concepts, interdisciplinary synthesis, and perspectives

open access: yesBiological Reviews, EarlyView.
ABSTRACT Carrion is a ubiquitous resource in both terrestrial and aquatic ecosystems, yet it has long been overlooked in ecological research. Over the past two decades, studies on carrion and the many organisms that exploit it have flourished, revealing not only wide‐ranging ecological functions but also significance far beyond ecology.
Marcos Moleón   +38 more
wiley   +1 more source

Vaccination for girls and women across the life course: Evidence‐based recommendations for clinical practice and policy

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Vaccination across the life course is a cornerstone of preventive health care for girls and women. Although WHO recommends completion of essential vaccines by adolescence, global coverage remains suboptimal. Vaccine‐preventable diseases—including HPV‐related cancers, vaginal, vulvar, anal, oropharyngeal, influenza, pertussis, hepatitis B ...
Hema Divakar   +13 more
wiley   +1 more source

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

open access: yesInterdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang   +13 more
wiley   +1 more source

Rabies virus glycoprotein variants display different patterns in rabies monosynaptic tracing

open access: yesFrontiers in Neuroanatomy, 2014
Rabies virus (RV) has been widely used to trace multi-synaptic neuronal circuits. The recent development of glycoprotein-deficient rabies virus (RV-ΔG) expressing various proteins has enabled analyses of both the structure and function of neuronal ...
Takuma eMori, Kinjiro eMorimoto
doaj   +1 more source

Evaluation of the marking duration of iophenoxic acid (IPA) derivatives in raccoons (Procyon lotor)

open access: yesThe Journal of Wildlife Management, EarlyView.
We evaluated the marking duration and intensity of iophenoxic acid (IPA) analogues in raccoon (Procyon lotor) serum following consumption of test doses encapsulated in a marshmallow or formulated into an oral rabies vaccine bait matrix. The IPA biomarkers demonstrated utility for evaluation of oral rabies vaccination baiting strategies targeting ...
Shylo R. Johnson   +7 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

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