Results 71 to 80 of about 66,201 (230)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

BIOTECHNOLOGICAL RESEARCH IN THE CREATION AND PRODUCTION OF ANTIRABIC VACCINES [PDF]

Biotechnologia Acta, 2021
Rabies is a neurological disease of a viral nature, leading to death. Rabies virus is an RNA virus that invades the central nervous system, leading to neuronal dysfunction. Timely vaccination can prevent the diseases development. Aim.
Krasnopolsky Yu. М., Pylypenko D. М.
doaj  

Drivers of bat researchers’ intent to adopt field hygiene practices

Conservation Biology, EarlyView.
Abstract Infectious disease is a growing threat to wildlife, with zoonotic transmission most likely at the human–wildlife interface. One underappreciated activity at this interface is fieldwork with wild animals, but associated risks can be mitigated through field hygiene (FH) practices, such as using personal protective equipment and other appropriate
Joanna L. Coleman, Ewan A. Macdonald, Abigail L. Rutrough, Tanja M. Straka, Todd D. Little, Zachary Stickley, Tigga Kingston   +6 more
wiley   +1 more source

New recombinant rabies vaccines

Биопрепараты: Профилактика, диагностика, лечение, 2018
The review covers problems of construction and production of new recombinant rabies vaccine. New approaches are being investigated to develop rabies vaccine and include methods of reverse genetic, production of virus antigens in plant cells cultures ...
E. S. Sedova, M. M. Shmarov
doaj  

Arctic-like Rabies Virus, Bangladesh

Emerging Infectious Diseases, 2012
Arctic/Arctic-like rabies virus group 2 spread into Bangladesh ≈32 years ago. Because rabies is endemic to and a major public health problem in this country, we characterized this virus group.
Khondoker Mahbuba Jamil, Kamruddin Ahmed, Moazzem Hossain, Takashi Matsumoto, Mohammad Azmat Ali, Sohrab Hossain, Shakhawat Hossain, Aminul Islam, Mohammad Nasiruddin, Akira Nishizono   +9 more
doaj   +1 more source

APRIL:TACI axis is dispensable for the immune response to rabies vaccination. [PDF]

, 2017
There is significant need to develop a single-dose rabies vaccine to replace the current multi-dose rabies vaccine regimen and eliminate the requirement for rabies immune globulin in post-exposure settings.
Alugupalli, Kishore R., Haley, Shannon L., Lytle, Andrew G., McGettigan, James P., Plummer, Joseph R., Tzvetkov, Evgeni P.   +5 more
core   +1 more source

The Final (Oral Ebola) Vaccine Trial on Captive Chimpanzees? [PDF]

, 2017
Could new oral vaccine technologies protect endangered wildlife against a rising tide of infectious disease? We used captive chimpanzees to test oral delivery of a rabies virus (RABV) vectored vaccine against Ebola virus (EBOV), a major threat to wild ...
Goetzmann, Jason E., Hasselschwert, Dana L., Kurup, Drishya, Schnell, Matthias J., Walsh, Peter D., Wirblich, Christoph   +5 more
core   +2 more sources

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Deforestation and Bovine Rabies Outbreaks in Costa Rica, 1985–2020

Emerging Infectious Diseases
In Latin America, rabies virus has persisted in a cycle between Desmodus rotundus vampire bats and cattle, potentially enhanced by deforestation. We modeled bovine rabies virus outbreaks in Costa Rica relative to land-use indicators and found spatial ...
Christie Jones, Amanda Vicente-Santos, Julie A. Clennon, Thomas R. Gillespie   +3 more
doaj   +1 more source

Zoonotic anxieties: The cultural politics of Nepal's quest for pandemic preparedness

Medical Anthropology Quarterly, EarlyView.
Abstract Based on fieldwork conducted in Nepal (2022–2024) and by paying attention to how local and transnational notions of epidemiological risk are deployed, this ethnography introduces the concept of “zoonotic anxieties” to make sense of the multi‐species relational ethos that contemporary global health regimes propose.
Max D. López Toledano, Hari Basnet, Anna Durrance‐Bagale, Natasha Howard   +3 more
wiley   +1 more source