Results 71 to 80 of about 33,698 (178)

First Report of Gray Foxes ( Urocyon cinereoargenteus ) Infected with Bat-Associated rabies Virus ( Desmodus rotundus rabies virus) in Costa Rica

Zoonoses
Rabies is a lethal zoonotic viral disease that affects mammals. Although Costa Rica has not reported any cases of canine rabies since 1987, cases of bat-transmitted rabies virus in domestic animals are recorded annually.
Josimar Estrella-Morales, Juan C. Alvarado-Fernández, Carolina Salas, Rocío González-Barrientos, Idania Chacón, Olga Aguilar, Juan M. Cordero-Solórzano, Bernal León   +7 more
doaj   +1 more source

Sufficient virus-neutralizing antibody in the central nerve system improves the survival of rabid rats

Journal of Biomedical Science, 2012
Background Rabies is known to be lethal in human. Treatment with passive immunity for the rabies is effective only when the patients have not shown the central nerve system (CNS) signs.
Liao Pi-Hung, Yang Hui-Hua, Chou Ping-Tse, Wang Ming-Hseng, Chu Po-Chun, Liu Hao-Li, Chen Li-Kuang   +6 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Barriers to Canine Rabies Vaccination in Nigeria: Implications for Rabies Elimination by 2030

Zoonoses and Public Health, Volume 73, Issue 5, Page 467-479, August 2026.
ABSTRACT Introduction Mass dog rabies vaccination is the most effective strategy for preventing human rabies and interrupting transmission. However, achieving high vaccination coverage in dog populations remains challenging in many low‐ and middle‐income countries (LMICs), due to multiple barriers.
Philip P. Mshelbwala, Bura T. Paul, Emmanuel O. Njoga, Solomon W. Audu, Musundwa Mugodi, Precious I. Okezie, Kinley Wangdi, Claude T. Sabeta, Charles E. Rupprecht   +8 more
wiley   +1 more source

Medium-term cryopreservation of rabies virus samples

Revista da Sociedade Brasileira de Medicina Tropical, 2013
Introduction The cryopreservation of rabies virus has been described in detail in the literature. To date, little information is available on the use of cryoprotective agents for cold preservation of this virus, and the available data focus only on short-
Tereza D'avila de Freitas Aguiar, Maria Fatima da Silva Teixeira, Edmara Chaves Costa, Allan Bezerra Vitaliano, Carlos Henrique de Andrade Teles, Igor Ciriaco Barroso, Ronaldo Pereira Dias, Nelio Batista de Moraes   +7 more
doaj   +1 more source

Oligosaccharides of the glycoprotein of rabies virus [PDF]

Journal of Virology, 1977
The number of oligosaccharide side chains on rabies virus glycoprotein (G-protein) was investigated. Analysis of glycopeptides obtained by protease digestion of desialated G-protein revealed three discrete glycopeptides. Comparison of the protease digestion products from desialated and from untreated G-protein indicated a heterogeneity among the ...
openaire   +2 more sources

A Study on the Ocular Infection with Rabies Virus in Mouse

Journal of Medical Microbiology and Infectious Diseases, 2014
Introduction: The most common mode of rabies virus transmission is through a bite wound or contact of broken skin with saliva of a rabid animal. Various other routes of virus transmission include exposure of mucous membranes (i.e.
Atefeh Pilehvar Zavareh, Mohammadreza Mahzounieh, Mohammadreza Shirzadi, Rouzbeh Bashar, Alireza Zavareh, Nader Howaizi, Firuzeh Farahtaj, Alireza Janani, Alireza Gholami   +8 more
doaj  

Short-interfering RNAs as antivirals against rabies

Brazilian Journal of Infectious Diseases
This study aimed to test in vitro a RNA-interference based antiviral approach for rabies with short-interfering RNAs (siRNAs) against rabies virus nucleoprotein mRNA.
Paulo Eduardo Brandão, Juliana Galera Castilho, Willian Fahl, Pedro Carnieli Jr., Rafael de Novaes Oliveira, Carla Isabel Macedo, Maria Luiza Carrieri, Ivanete Kotait   +7 more
doaj   +1 more source

Rabies Virus Infection: A Case Series and Literature Review

Journal of Pediatrics Review, 2022
Background: Rabies is a fatal and often neglected disease leading to encephalomyelitis following a bite by an infected mammal. According to the necessity of rabies disease in Iran, we present four cases of rabies virus infection.
Shiva Shadani, Fahimeh Ghasemi, Mahsa Kamali, Mohammad Reza Navaeifar, Ahmad Alikhani, Shahriar Alian, Alireza Davoudi Badabi, Mohammad Sadegh Rezai   +7 more
doaj  

Mechanisms of escape phenomenon of spinal cord and brainstem in human rabies

BMC Infectious Diseases, 2005
Background Rabies virus preferentially involves brainstem, thalamus and spinal cord in human furious and paralytic rabies beginning in the early stage of illness. Nevertheless, rabies patient remains alert until the pre-terminal phase.
Wacharapluesadee Supaporn, Shuangshoti Shanop, Ruangvejvorachai Preecha, Juntrakul Sasiwimol, Hemachudha Thiravat   +4 more
doaj   +1 more source