Results 41 to 50 of about 71,357 (285)

Antiviral Ranpirnase TMR-001 Inhibits Rabies Virus Release and Cell-to-Cell Infection In Vitro

Viruses, 2020
Currently, no rabies virus-specific antiviral drugs are available. Ranpirnase has strong antitumor and antiviral properties associated with its ribonuclease activity.
Todd G. Smith, Felix R. Jackson, Clint N. Morgan, William C. Carson, Brock E. Martin, Nadia Gallardo-Romero, James A. Ellison, Lauren Greenberg, Thomas Hodge, Luis Squiquera, Jamie Sulley, Victoria A. Olson, Christina L. Hutson   +12 more
doaj   +1 more source

Antigenic and genetic characterization of a divergent African virus, Ikoma lyssavirus [PDF]

, 2014
In 2009, a novel lyssavirus (subsequently named Ikoma lyssavirus, IKOV) was detected in the brain of an African civet (Civettictis civetta) with clinical rabies in the Serengeti National Park of Tanzania.
Alejandro Nunez, Alison J. Peel, Anthony R. Fooks, Ashley C. Banyard, Aubert, Brookes, Charles E. Rupprecht, Daniel Hicks, Daniel L. Horton, David Selden, Dean, Denise A. Marston, Dietzgen, Emma Wise, Estes, Ivan V. Kuzmin, Lodmell, Markotter, Sarah Cleaveland, Tiziana Lembo, Turmelle, Wilbur   +21 more
core   +2 more sources

Determination of freedom-from-rabies for small Indian mongoose populations in the United States Virgin Islands, 2019-2020.

PLoS Neglected Tropical Diseases, 2021
Mongooses, a nonnative species, are a known reservoir of rabies virus in the Caribbean region. A cross-sectional study of mongooses at 41 field sites on the US Virgin Islands of St. Croix, St. John, and St. Thomas captured 312 mongooses (32% capture rate)
A Springer Browne, Hannah M Cranford, Clint N Morgan, James A Ellison, Are Berentsen, Nicholas Wiese, Alexandra Medley, John Rossow, Leanne Jankelunas, Alan S McKinley, Claudia D Lombard, Nicole F Angeli, Thomas Kelley, Jennifer Valiulus, Bethany Bradford, Valicia J Burke-France, Cosme J Harrison, Irene Guendel, Marissa Taylor, Gerard L Blanchard, Jeffrey B Doty, David J Worthington, David Horner, Keith R Garcia, Joseph Roth, Brett R Ellis, Kristine M Bisgard, Ryan Wallace, Esther M Ellis   +28 more
doaj   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Clonal analysis of a human antibody response. Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG, and IgA to rabies virus. [PDF]

, 1990
We quantitated and characterized the changes in the human B cell repertoire, at the clonal level, before and after immunization with rabies virus. Moreover, we generated 10 monoclonal cell lines producing IgM, IgG, and IgA antibodies to the virus.
Casali, P, Goldfarb, IS, Gore, M, Harindranath, N, Koprowski, H, Notkins, AL, Ueki, Y   +6 more
core  

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Frequency analysis of cytolytic T cell precursors (CTL-P) generated in vivo during lethal rabies infection of mice. I. Distinction of CTL-P with different interleukin 2 sensitivity [PDF]

, 1982
The aim of this study was to determine the number and state of activity of cytolytic T lymphocytes (CTL) and their precursors (CTL-P) present in vivo during the early stages of viral infection. The local response to lethal infection with rabies virus was
Cerottini, Fischer Lindahl, Gillis, Hardt, Komatsu, Koszinowski, Lagrange, Lefkovits, Miller, Plate, Ryser, Schneider, Skinner, Smith, Smith, Teh, Wagner, Wagner, Wiktor, Wiktor, Wiktor, Zinkernagel   +21 more
core   +1 more source

Major Causes of Rabies Outbreak in Pastoral Areas of the Somali Region and Importance of the One Health Approach

Animal Research and One Health, EarlyView.
Rabies Transmission and Control in the Somali Region. Introduction: Rabies is a fatal zoonotic disease caused by the Lyssavirus, posing a significant threat to both wildlife and public health in the Somali Region of Ethiopia. Key Points: 1. Primary Hosts: Wild carnivores such as foxes, jackals, raccoons, skunks, bats, and honey badgers are the main ...
Hassan Abdi Hussein
wiley   +1 more source

Rabies on the Last Frontier: A Phylogeographical Look at Red (Vulpus vulpus) and Arctic (Vulpus lagopus) Fox with Respect to Mitochondrial DNA and the Spatial Diffusion of Rabies [PDF]

, 2012
Vulpus vulpus and Vulpus lagopus are terrestrial animals that live in Alaska. They are also common carriers of the rabies virus. It has been determined that there are three different clades of rabies in Alaska being vectored by these two species of fox,
Clement, Christopher J.
core  

Landscape attributes governing local transmission of an endemic zoonosis: rabies virus in domestic dogs [PDF]

, 2018
Landscape heterogeneity plays an important role in disease spread and persistence, but quantifying landscape influences and their scale dependence is challenging.
Biek, Roman, Brunker, Kirstyn, Fooks, Anthony R., Hampson, Katie, Lemey, Philippe, Lugelo, Ahmed, Marston, Denise A., Ngeleja, Chanasa   +7 more
core   +1 more source