A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis
The dynamic interplay between central respiratory chemoreceptors and the respiratory central pattern generator is essential for maintaining stable respiratory rhythm and patterns, particularly during sleep. This study offers novel insights into the anatomical, molecular, and functional characteristics of a medullary network involving the nucleus ...
Tianjiao Deng+16 more
wiley +1 more source
Advanced Virus Monitoring and Analysis System [PDF]
This research proposed an architecture and a system which able to monitor the virus behavior and classify them as a traditional or polymorphic virus. Preliminary research was conducted to get the current virus behavior and to find the certain parameters which usually used by virus to attack the computer target.
arxiv
Improving the identification of antigenic sites in the H1N1 Influenza virus through accounting for the experimental structure in a sparse hierarchical Bayesian model [PDF]
Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between pairs of virus strains to identify important antigenic sites on the surface of the influenza A(H1N1) virus through
arxiv +1 more source
Spatio-temporal Use of Oral Rabies Vaccines in Fox Rabies Elimination Programmes in Europe. [PDF]
In Europe, the elimination of wildlife rabies using oral rabies vaccination [ORV] of foxes for more than 30 years has been a success story. Since a comprehensive review on the scope of the different oral rabies vaccine baits distributed across Europe has
Thomas F Müller+4 more
doaj +1 more source
Clonal analysis of a human antibody response. Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG, and IgA to rabies virus. [PDF]
We quantitated and characterized the changes in the human B cell repertoire, at the clonal level, before and after immunization with rabies virus. Moreover, we generated 10 monoclonal cell lines producing IgM, IgG, and IgA antibodies to the virus.
Casali, P+6 more
core
A Bayesian approach for inferring the dynamics of partially observed endemic infectious diseases from space-time-genetic data [PDF]
We describe a statistical framework for reconstructing the sequence of transmission events between observed cases of an endemic infectious disease using genetic, temporal and spatial information.
Hampson, Katie+6 more
core +3 more sources
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge+16 more
wiley +1 more source
Landscape attributes governing local transmission of an endemic zoonosis: rabies virus in domestic dogs [PDF]
Landscape heterogeneity plays an important role in disease spread and persistence, but quantifying landscape influences and their scale dependence is challenging.
Biek, Roman+7 more
core +1 more source
Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang+3 more
wiley +1 more source
Fighting Zoonotic, Rabies and Public Health in Colonial India [PDF]
Rabies is the oldest Zoonotic diseases in the world and one of the most important Zoonotic diseases in India. It was one of the most difficult problems confronted both by the medical and veterinary authorities in colonial India.
Rahaman, S. M. (Sk)
core +3 more sources