Results 21 to 30 of about 6,323 (205)
Ukraine: Sleepwalking into the Unknown
Cadmus, 2022 The article raises some fundamental questions concerning the Ukraine-Russia war: why is the UN not intervening to bring peace? What does the West want? These are all questions that we should be asking urgently, but don’t.
Renzo Cianfanelli
doaj
Isolation and characterization of monoacetyldiglycerides from bovine udder
Journal of Lipid Research, 1999 Monoacetyldiglycerides (MADGs) were isolated from an animal tissue, bovine udder, by solvent extraction and silica gel column chromatography. Monoacetyldiglyceride structures were identified using a variety of 1-D and 2-D NMR techniques and collision ...
Jin-Kyung Limb +3 more
doaj +1 more source
Switching to Rac and Rho [PDF]
Structure, 1995 Could the recent elucidation of the structure of the Rap-Raf complex have been the first glimpse of a universal arrangement between GTPase switches and kinase cascades, as a number of recent reports show that Ras is not unique in its ability to start a signalling 'chain reaction'?
Block, Christoph, Wittinghofer, Alfred
openaire +2 more sources
Marine Drugs, 2022 A series of twenty-three linear and branched chain mono acetylene lipids were isolated from the Caribbean Sea sponge Cribrochalina vasculum. Seventeen of the compounds, 1–17, are new, while six, 18–23, were previously characterized from the same sponge ...
Dimitry Kovalerchik +7 more
doaj +1 more source
Case Studies in Construction Materials, 2022 In this paper, the most-concerned questions of recycled aggregate concrete (RAC) application, i.e., the structural safety performance, the availability of design code and project experience, and ecological and economic costs, are overviewed, aiming to ...
Jianzhuang Xiao +3 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues
Cell Reports, 2014 The small G protein family Rac has numerous regulators that integrate extracellular signals into tight spatiotemporal maps of its activity to promote specific cell morphologies and responses.
Anna-Karin E. Johnsson +15 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Rac in the Act of Forgetting [PDF]
Cell, 2010 Forgetting has been thought to occur as a result of the natural decay of the neuronal changes induced by learning or because of interference from other cognitive functions. In this issue, Shuai et al. (2010) find that the small G protein Rac may function as a switch for remembering versus forgetting.
openaire +2 more sources