Results 21 to 30 of about 42,168 (252)

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]

open access: yes, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Liliana Schäfer   +56 more
core   +1 more source

Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt

open access: yesBiomolecular Concepts, 2015
Both cell-cell and cell-matrix adhesion are important for epithelial cell differentiation and function. Classical cadherins mediate cell to cell interactions and are potent activators of the signal transducer and activator of transcription (Stat3 ...
Niit Maximilian   +6 more
doaj   +1 more source

Rhythmic auditory cueing in atypical parkinsonism: A pilot study

open access: yesFrontiers in Neurology, 2022
Rhythmic auditory cueing (RAC) can improve gait parameters in neurological disorders such as Parkinson's disease and stroke. However, there is a lack of research on the effects of RAC in patients with atypical parkinsonian disorders (APD).
Alexander Pantelyat   +9 more
doaj   +1 more source

Rac-GEF/Rac Signaling and Metastatic Dissemination in Lung Cancer [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
Lung cancer is the leading cause of cancer-related deaths worldwide, with non-small cell lung cancer (NSCLC) representing ∼85% of new diagnoses. The disease is often detected in an advanced metastatic stage, with poor prognosis and clinical outcome. In order to escape from the primary tumor, cancer cells acquire highly motile and invasive phenotypes ...
Mariana Cooke   +2 more
openaire   +3 more sources

RAC drawings in subcubic area [PDF]

open access: yesInformation Processing Letters, 2020
In this paper, we study tradeoffs between curve complexity and area of Right Angle Crossing drawings (RAC drawings), which is a challenging theoretical problem in graph drawing. Given a graph with $n$ vertices and $m$ edges, we provide a RAC drawing algorithm with curve complexity $6$ and area $O(n^{2.75})$, which takes time $O(n+m)$.
Zahed Rahmati, Fatemeh Emami
openaire   +4 more sources

Contribuições e Limitações de Revisões Narrativas e Revisões Sistemáticas na Área de Negócios

open access: yesRAC: Revista de Administração Contemporânea, 2019
Neste editorial, o segundo do volume 23 da Revista de Administração Contemporânea (RAC), julguei oportuno abordar um assunto que se apresenta sensivelmente relevante para dirimir esforços redundantes de pesquisa no campo de negócios: as duas maneiras ...
Wesley Mendes-Da-Silva
doaj   +1 more source

Ukraine: Sleepwalking into the Unknown

open access: yesCadmus, 2022
The article raises some fundamental questions concerning the Ukraine-Russia war: why is the UN not intervening to bring peace? What does the West want? These are all questions that we should be asking urgently, but don’t.
Renzo Cianfanelli
doaj  

Switching to Rac and Rho [PDF]

open access: yesStructure, 1995
Could the recent elucidation of the structure of the Rap-Raf complex have been the first glimpse of a universal arrangement between GTPase switches and kinase cascades, as a number of recent reports show that Ras is not unique in its ability to start a signalling 'chain reaction'?
Block, Christoph, Wittinghofer, Alfred
openaire   +2 more sources

Isolation and characterization of monoacetyldiglycerides from bovine udder

open access: yesJournal of Lipid Research, 1999
Monoacetyldiglycerides (MADGs) were isolated from an animal tissue, bovine udder, by solvent extraction and silica gel column chromatography. Monoacetyldiglyceride structures were identified using a variety of 1-D and 2-D NMR techniques and collision ...
Jin-Kyung Limb   +3 more
doaj   +1 more source

Pesquisa de Impacto: Teoria e Prática no Mundo Corporativo

open access: yesRAC: Revista de Administração Contemporânea, 2023
O impacto que uma pesquisa causa na sociedade não pode ser medido apenas pela quantidade de atenção (citações) que essa pesquisa atrai. Uma pesquisa de alto impacto é aquela que tem alta relevância para a sociedade, sendo útil para fortalecer ou ...
Orleans Silva Martins
doaj   +1 more source

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