Results 41 to 50 of about 3,395,263 (313)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A New Look at the Old Race Language: Rethinking Race and Exclusion in Social Policy [PDF]

open access: yes, 1993
This essay is an examination of the use of the notion “race current in American social science literature and public discourse. It argues that the current assumptions of “race are mistaken and lead to misunderstanding and misdirected social policy.
Ngin, ChorSwang
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Bone: An Acute Buffer of Plasma Sodium during Exhaustive Exercise?

open access: yes, 2013
Both hyponatremia and osteopenia separately have been well documented in endurance athletes. Although bone has been shown to act as a “sodium reservoir” to buffer severe plasma sodium derangements in animals, recent data have suggested a similar function
Hew-Butler, Tamara   +2 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Not in Our World: A Perspective of Community Organizing Against Hate

open access: yesJournal of Hate Studies, 2002
On Sept. 11, 2001, Americans were brutalized by an undeniable statement of hatred that made an indelible impression on not just its thousands of victims, but on the consciousness of the whole world.
Bill Wassmuth, M.J. Bryant
doaj   +1 more source

Perceiving the Anthropocene as a Public Health Risk via Visual Culture

open access: yesEuropean Journal of Creative Practices in Cities and Landscapes, 2023
There is widespread scientific and cultural evidence that Earth’s planetary boundaries are being exceeded in irreparable ways due to unsustainable behavior in the Global North’s resource-hungry nations in particular, but responsiveness to the climate ...
Daniel A. Finch-Race
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Urban Built Environment and Mobility in Older Adults: A Comprehensive Review

open access: yesJournal of Aging Research, 2011
Mobility restrictions in older adults are common and increase the likelihood of negative health outcomes and premature mortality. The effect of built environment on mobility in older populations, among whom environmental effects may be strongest, is the ...
Andrea L. Rosso   +2 more
doaj   +1 more source

Intrusion Detection Systems for Community Wireless Mesh Networks [PDF]

open access: yes, 2008
Wireless mesh networks are being increasingly used to provide affordable network connectivity to communities where wired deployment strategies are either not possible or are prohibitively expensive.
Hutchison, David   +3 more
core   +1 more source

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