Results 101 to 110 of about 1,384,185 (280)
Race/class : Jamaica's discourse of heritable identity
NWIG, 1994 Argues that Jamaican notions of 'race' and 'class' can be rendered as a discourse of heritable biological and environmental identity. There has been a movement in the meaning of colour categories from an emphasis on biology, to a greater emphasis on ...
Diane J. Austin-Broos
doaj
Human races are not like dog breeds: refuting a racist analogy
Evolution: Education and Outreach, 2019 In 1956, evolutionary biologist J.B.S. Haldane posed a question to anthropologists: “Are the biological differences between human groups comparable with those between groups of domestic animals such as greyhounds and bulldogs…?” It reads as if it were ...
Heather L. Norton +4 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Bacteriophages of Myxococcus xanthus, a Social Bacterium
Viruses, 2018 Bacteriophages have been used as molecular tools in fundamental biology investigations for decades. Beyond this, however, they play a crucial role in the eco-evolutionary dynamics of bacterial communities through their demographic impact and the source ...
Marie Vasse, Sébastien Wielgoss
doaj +1 more source
Beyond English-Only Reading Comprehension: Experiments in Zero-Shot Multilingual Transfer for Bulgarian [PDF]
arXiv, 2019 Recently, reading comprehension models achieved near-human performance on large-scale datasets such as SQuAD, CoQA, MS Macro, RACE, etc. This is largely due to the release of pre-trained contextualized representations such as BERT and ELMo, which can be fine-tuned for the target task. Despite those advances and the creation of more challenging datasets,
arxiv
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Eating the [M]Other: Exploring Swedish Adoption Consumption Fantasies
Genealogy, 2019 Drawing on bell hooks’ classic essay Eating the Other: Desire and Resistance, this article discusses ethnic consumption fantasies of white Swedish international adopters.
Richey Wyver
doaj +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Gene and Gene-Set Analysis for Genome-Wide Association Studies [PDF]
arXiv, 2013 Genome-wide association studies (GWAS) have identified hundreds of loci at very stringent levels of statistical significance across many different human traits. However, it is now clear that very large samples (n~10^4-10^5) are needed to find the majority of genetic variants underlying risk for most human diseases.
arxiv
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source