Results 81 to 90 of about 504,265 (307)

Recent advances in imaging subcellular processes [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Cell biology came about with the ability to first visualize cells. As microscopy techniques advanced, the early microscopists became the first cell biologists to observe the inner workings and subcellular structures that control life. This ability to see
Kenneth A. Myers   +1 more
doaj   +1 more source

Unlearning Fear Out-Group Others [PDF]

open access: yes, 2009
Maroney describes a neuroscientific fear-extinction study as preliminary evidence supporting the notion that out-group hostilities might be influenced by biological predispositions.
Maroney, Terry A.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Rhythmidia: A modern tool for circadian period analysis of filamentous fungi.

open access: yesPLoS Computational Biology
Circadian rhythms are ubiquitous across the kingdoms of life and serve important roles in regulating physiology and behavior at many levels. These rhythms occur in ~24-hour cycles and are driven by a core molecular oscillator.
Alex T Keeley   +2 more
doaj   +1 more source

Illuminating systematic differences in no job offers for STEM doctoral recipients.

open access: yesPLoS ONE, 2020
This study examines differences across demographic subgroups in the phenomenon of recent doctoral recipients seeking work but having no job offers for employment.
Timothy J Kinoshita   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Race/class : Jamaica's discourse of heritable identity

open access: yesNWIG, 1994
Argues that Jamaican notions of 'race' and 'class' can be rendered as a discourse of heritable biological and environmental identity. There has been a movement in the meaning of colour categories from an emphasis on biology, to a greater emphasis on ...
Diane J. Austin-Broos
doaj  

Session 1: Eugenics Narrative and Reproductive Engineering [PDF]

open access: yes, 2002
Proceedings of the Pittsburgh Workshop in History and Philosophy of Biology, Center for Philosophy of Science, University of Pittsburgh, March 23-24 2001 Session 1: Eugenics Narrative and Reproductive ...
Diane, Paul, Lennox, James, Tabery, Jim
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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