Results 41 to 50 of about 503,830 (343)

Race as the basis of 'völkisch' historiography

open access: yesMètode Science Studies Journal: Annual Review
This article addresses changes in scientific thought in the 19th and early 20th centuries in Germany and Austria, which favoured the development of a historiography based on concepts of race. The rise of the natural sciences and particularly, of biology
Othmar Ploeckinger
doaj   +1 more source

N.C. Medicaid Reform: A Bipartisan Path Forward [PDF]

open access: yes, 2017
The North Carolina Medicaid program currently constitutes 32% of the state budget and provides insurance coverage to 18% of the state’s population. At the same time, 13% of North Carolinians remain uninsured, and even among the insured, significant ...
Rice, Allison, Richman, Barak D.
core   +1 more source

Molecular cloning and transcriptional activity of a new Petunia calreticulin gene involved in pistil transmitting tract maturation, progamic phase, and double fertilization [PDF]

open access: yes, 2013
Calreticulin (CRT) is a highly conserved and ubiquitously expressed Ca2+-binding protein in multicellular eukaryotes. As an endoplasmic reticulum-resident protein, CRT plays a key role in many cellular processes including Ca2+ storage and release ...
A Christensen   +59 more
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Molecular Biology of Precision Medicine in JDC [PDF]

open access: yes, 2015
On April 29, 2015, the Computational Medicine Center, The Sidney Kimmel Cancer Center, The Wills Eye Hospital, and The Jefferson Graduate School of Biomedical Sciences presented a one-day event: The Molecular Biology of Precision Medicine: Gender ...
Kipnis, MSI, Daniel G.
core   +1 more source

Medication Risk and Polypharmacy in Minority Older Adults [PDF]

open access: yes, 2020
Medication Risk and Polypharmacy in Minority Older Adults Rusha Patel, Depts. of Biology and Chemistry, with Dr. Youssef Roman, VCU School of Pharmacy, Dr. Elvin Price, VCU School of Pharmacy, and Dr.
Patel, Rusha
core   +1 more source

Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host [PDF]

open access: yes, 2013
Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals.
A Bridgen   +73 more
core   +3 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Longitudinal NMR-based Metabolomics Analysis of Male Mountain Ultramarathon Runners: New Perspectives for Athletes Monitoring and Injury Prevention

open access: yesSports Medicine - Open
Background The aim of this study was to explore how a metabolomic approach could provide valuable information on changes in the athletes' metabolome during a mountain ultramarathon race.
Matthieu Schoumacher   +17 more
doaj   +1 more source

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