Results 101 to 110 of about 766,787 (401)

Black Lives Matter: Decrypting Encrypted Racism [PDF]

open access: yes, 2017
The agitation of the Black Lives Matter movement has dominated the public discourse in the United States. Mobilized against the killing of unarmed black people, the movement and their sympathizers have made a series of demands for justice and dignity for
Ugorji, Basil
core   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason   +12 more
wiley   +1 more source

Racism in Finnish basic education: discursive depoliticization through policies

open access: yesNordic Journal of Studies in Educational Policy
There are legislation and policies promoting equality and non-discrimination in Finnish schools, yet racism remains part of everyday life in schools and school staff find it difficult to address.
Jenni Helakorpi, Gunilla Holm
doaj   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

open access: yesAdvanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng   +10 more
wiley   +1 more source

PUTTING RACIAL EQUALITY ONTO THE GLOBAL HUMAN RIGHTS AGENDA

open access: yesSur: International Journal on Human Rights, 2018
Equality is generally marginalized within the global human rights agenda, and among those who wield power in the formation and execution of this agenda.
E. Tendayi Achiume
doaj  

Using simulation-based education to enhance anti-racism learning in nursing

open access: yesRevista Enfermagem Contemporânea
OBJECTIVE: To determine whether simulation-based education promotes anti-racism learning among nursing students. METHODS: This descriptive qualitative study explored how simulation-based education could support anti-racism education in undergraduate ...
Heather Epp   +5 more
doaj   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei   +11 more
wiley   +1 more source

The Effects of Gender and Self Construal on Perception of Racism

open access: yes, 2016
When looking into the idea of if one\u27s gender and their self-construal has an effect on how they perceive racism, we hypothesize that women will take a more interdependent self-construal and men will take a more independent self-construal.
Schapiro, Lauren S.   +2 more
core  

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

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