Results 81 to 90 of about 274,321 (351)
Advanced Materials, EarlyView.Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park +15 more
wiley +1 more source
, 2020 Racism, conceptualised as unfair and avoidable disparities in power, resources, capacities or opportunities across ethnic, racial, religious or cultural differences, can manifest in cognitive beliefs, feelings or behaviours.
A Piyarathne (17114194) +8 more
core
Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq
Advanced Science, EarlyView.Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su +10 more
wiley +1 more source
Combating Racism and Becoming An Ally of Anti-Racist Group. [PDF]
, 2003 Habiba Zaman led a workshop aimed at breaking down racism. The main issues addressed was acknowledgment of different kinds of privileges and oppressions; definition and concept of racism; where does racism come from; reflections based on one\u27s own ...
SFU Women\u27s Studies Department +1 more
core
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
Advanced Science, EarlyView.An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
Sociodemographic variation in experiences with medication shortages among US adults
Preventive Medicine ReportsObjective: To investigate sociodemographic factors associated with prescribed and over-the-counter medication shortage experiences. Methods: We analyzed repeated cross-sectional data from the 2023 US Census Household Pulse Survey, a nationwide survey of ...
Jinrui Fang +6 more
doaj +1 more source
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Racism in German healthcare: uncovering the construction and silencing of the “other”
Frontiers in Public HealthWhile the impact of racism on healthcare interactions has been researched extensively in many parts of the world, substantive studies on healthcare-related racism in Europe, and particularly in Germany, remain scarce.
Tanja Gangarova +2 more
doaj +1 more source