Results 61 to 70 of about 623,879 (355)
Advanced Healthcare Materials, EarlyView.Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae +9 more
wiley +1 more source
Advanced Materials, EarlyView.Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source
Citizenship Education as Placebo: 'standards', institutional racism and education policy [PDF]
, 2006 The issue of 'Institutional Racism' briefly rose to the top of the policy agenda when, in 1999, the British government was faced with a damning report into the circumstances surrounding the racist murder of Stephen Lawrence (an 18 year old Black college ...
Gillborn, David
core +2 more sources
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Reporting racism: what you say matters [PDF]
The Victorian Equal Opportunity and Human Rights Commission has conducted research to learn more about the experiences of racism and racial and religious vilification in Victoria.
core +3 more sources
Is There a Case for Mandatory Reporting of Racism in Schools?
The Australian Journal of Indigenous Education, 2017 This paper explores how the colonial hegemony of racism in Australia could be disrupted in schools by introducing mandatory reporting of racism by teachers in Australia, and addresses the benefits and risks of mandatory reporting of racism.
Glenn Auld
doaj +1 more source
Building resilience in the face of racism: options for anti-racism strategies [PDF]
This paper recommends incorporating a focus on resilience in anti-racism strategies and suggest a framework for doing so which builds on the factors understood to promote resilience in those vulnerable to racism.
Rivkah Nissim
core
Critique [of Racism and the Canadian State by Daiva K. Stasiulis] [PDF]
, 1985 Stasiulis\u27s two-part essay offers a critique of the policies on immigration and racism pursued by the Canadian government during the past decade or so.
Hoglund, A. William
core +1 more source
Advanced Science, EarlyView.This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong +6 more
wiley +1 more source
Perceived racial discrimination over the life course and financial stress
Discover Social Science and HealthPurpose To quantify the associations between perceived racial discrimination over the life course and financial stress. Methods The data are from the 2023 Survey of Racism and Public Health, a cross-sectional survey of adults.
Jonathan N. Odumegwu +4 more
doaj +1 more source