Results 141 to 150 of about 6,657,503 (334)

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Landslide Classification from Synthetic Aperture Radar Images Using Convolutional Neural Network with Multichannel Information

, 2020
Shingo Mabu, Yoshiaki Nakayama, Takashi Kuremoto   +2 more
openalex   +2 more sources

A Clutter Suppression Method Based on LSTM Network for Ground Penetrating Radar [PDF]

, 2022
Jianrong Geng, Juan He, Hongxia Ye, Zhan Bin   +3 more
openalex   +1 more source

Structure‐Dependent Resonant Frequency Engineering of Textile Tactile Sensors Toward Rapid and Precise Braille Recognition Surpassing Human Sensation

Advanced Science, EarlyView.
A resonant frequency engineering strategy is proposed to modulate the sensibility of piezoresistive textile‐based tactile sensor. It achieves simultaneous detection of static pressure and dynamic vibrations across an unprecedented bandwidth of 5–600 Hz, surpassing human sensation, therefore enables rapid and precise braille recognition.
Xianhong Zheng, Runrun Zhang, Yu Shi, Zhao Zhang, Guiyang Li, Zhengliang Shang, Xin Liu, Fan Zhao, Sheng Hu, Ran Xu, Shuai Wang, Zhiqi Zhao, Zhi Liu, Lihua Zou, Xu Han, Zongqian Wang, Wei Huang, Gengzhi Sun   +17 more
wiley   +1 more source

Machine Learning Driven Window Blinds Inspired Porous Carbon‐Based Flake for Ultra‐Broadband Electromagnetic Wave Absorption

Advanced Science, EarlyView.
Inspired by the regulation mechanism of window blinds, this study designs an electromagnetic wave‐absorbing metamaterial. By introducing the magneto‐electric coupling concept and integrating it with an artificial intelligence‐based data‐driven collaborative optimization strategy, the material optimizes impedance matching performance and enhances loss ...
Zhe Wang, Wanchong Li, Lu Feng, Zaiqing Yang, Shicheng Jin, Dongxu Zhao, Xiaoyong Wu, Yan Wang, Yu Mao, Jinsong Zhang   +9 more
wiley   +1 more source

Dilution Effect for High‐Performance Multiple‐Component Near‐Infrared Organic Photodetectors

Advanced Science, EarlyView.
The dilution effect in multi‐component organic photodetector effectively suppresses non‐radiative decay and minimizes dark current, while energy‐level‐offset‐governed electron transfer between acceptors maintains efficient charge transport. This synergistic mechanism collectively enables remarkable device performance, including high detectivity and ...
Zhuang Li, Xunchang Wang, Xiaosong Qiu, Xinpeng Yang, Linming Bi, Jin Chen, Qian Wang, Yurong He, Jingyi Xiong, Renqiang Yang   +9 more
wiley   +1 more source

Extended Polarimetric Observations of Chaff using the WSR-88D Weather Radar Network [PDF]

, 2022
James M. Kurdzo, Betty J. Bennett, John Y. N. Cho, Michael F. Donovan   +3 more
openalex   +1 more source

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source