Results 191 to 200 of about 71,414 (262)

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

open access: yesMed Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen   +10 more
wiley   +1 more source

Efficacy and safety of arterial blood gas analysis via distal radial artery in children. [PDF]

open access: yesFront Pediatr
Yang L   +8 more
europepmc   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg   +2 more
wiley   +1 more source

5D Flow MRI Reveals Respiration‐Driven Changes in Blood Flow Energetics in Congenital Heart Disease

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Hemodynamic monitoring is essential for patients with right‐sided congenital heart disease (CHD). Respiration may have an increased impact on pulmonary flow in these patients that cannot be assessed by standard tools including 4D flow MRI. This study uses 5D flow MRI to assess respiratory‐cycle variations in flow energetics in patients
Thara Nallamothu   +7 more
wiley   +1 more source

Comparing Two Distal Radial Hemostatic Devices for Radial Artery Patency Post-TACE: A Randomized Trial. [PDF]

open access: yesCardiovasc Intervent Radiol
Lee CC   +7 more
europepmc   +1 more source

VQ‐Wave: A Physics‐Driven Spatiotemporal Deep Learning Approach for Noncontrast‐Enhanced Lung Ventilation and Perfusion MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a robust deep learning framework for noncontrast‐enhanced functional lung MRI, overcoming the limitations of spectral decomposition in the presence of physiological nonstationarity. Methods We introduce VQ‐Wave (Ventilation/Q‐perfusion Waveform‐based Assessment of Variable Evolutions), a physics‐driven spatiotemporal ...
Grzegorz Bauman   +3 more
wiley   +1 more source

Ultrafast fMRI Detects Age‐Related Changes in Harmonics of Cardiac Pulsations in the Brain at 7 T

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Aging impacts pulsatility of blood vessels in the brain, reflecting vascular health. Resolving characteristics of cardiac pulsatility requires faster acquisitions than traditional fMRI. An ultrafast fMRI method was developed and applied to sample several harmonics of cardiac pulsations at 7 T.
Charles Marchini   +5 more
wiley   +1 more source

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