Results 41 to 50 of about 540,445 (288)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Radial basis function networks with partially classified data [PDF]

, 1999
The problem of estimating a classification rule with partially classified observations, which often occurs in biological and ecological modelling, and which is of major interest in pattern recognition, is discussed.
MORLINI, Isabella
core   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Radial basis function neural networks: a topical state-of-the-art survey

Open Computer Science, 2016
Radial basis function networks (RBFNs) have gained widespread appeal amongst researchers and have shown good performance in a variety of application domains. They have potential for hybridization and demonstrate some interesting emergent behaviors.
Dash Ch. Sanjeev Kumar, Behera Ajit Kumar, Dehuri Satchidananda, Cho Sung-Bae   +3 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

SINTESA EKSPRESI WAJAH DENGAN MENGGUNAKAN RADIAL BASIS FUNCTION NETWORK

JUTI: Jurnal Ilmiah Teknologi Informasi, 2003
Pada penelitian yang sebelumnya [4] telah dilakukan penelitian tentang letak-letak (koordinat) facial characteristic points (FCP) yang digunakan sebagai dasar untuk mengenali ekspresi-ekspresi wajah manusia.
Wiwik Anggraeni, Handayani Tjandrasa
doaj   +1 more source

A Novel Reliability Analysis Approach With Collaborative Active Learning Strategy-Based Augmented RBF Metamodel

IEEE Access, 2020
Metamodels in lieu of time-demanding performance functions can accelerate the reliability analysis effectively. In this paper, we propose an efficient collaborative active learning strategy-based augmented radial basis function metamodel (CAL-ARBF), for ...
Yanxu Wei, Guangchen Bai, Lu-Kai Song
doaj   +1 more source

Compactly supported radial basis functions: how and why? [PDF]

, 2012
The use of radial basis functions have attracted increasing attention in recent years as an elegant scheme for high-dimensional scattered data approximation, an accepted method for machine learning, one of the foundations of mesh-free methods, an ...
Zhu, S.
core   +3 more sources

Magnetic Modelling of Synchronous Reluctance and Internal Permanent Magnet Motors Using Radial Basis Function Networks [PDF]

, 2018
The general trend toward more intelligent energy-aware ac drives is driving the development of new motor topologies and advanced model-based control techniques.
Ortombina, L., Tinazzi, F., Zigliotto, M.   +2 more
core   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source