Results 41 to 50 of about 37,382 (300)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Evaluation of bearing capacity due to radial expansion using expanding piles [PDF]

, 2013
The engineering community is familiar with different techniques to improve the bearing capacity and settlement characteristics of weak cohesive soils. Preload piers or expanding piles are newly invented method for improving soft soils by means of radial ...
Molkaraie, Pouya
core  

Analisis Pengaruh Jumlah Kutub, Besar Arus, dan Radial Clearance terhadap Gaya Radial pada Active Magnetic Bearing [PDF]

, 2020
Magnetic bearing dibagi menjadi dua jenis yaitu passive magnetic bearing dan active magnetic bearing. Pada tipe passive magnetic bearing beban yang dapat ditumpu tidak dapat bervariasi, bergantung pada kemampuan material magnet yang dipilih.
Iffagano, Muh Iqra Al Hamidy
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

CHARACTERISTIC STUDY FOR THE HETEROGENEOUS ROLLING BEARING MATCH WAY

Jixie qiangdu, 2015
When angular contact ball bearings match together,due to high demand of manufacturing and installation precision,only increasing the number of angular contact ball bearings to increase the radial bearing capacity has great limitations.Therefore,it was ...
WU KaiSong, DENG Tao, CAI Can, FENG Yan
doaj  

Investigation of Stress Variation in Push-the-Bit Rotary Steering Bearings Under Weight on Bit and Push Forces

Cejing jishu
As the key component of the push-the-bit rotary steerable system, the accuracy and reliability of the bearing system directly affect the control accuracy and drilling efficiency of the drilling tool on the borehole trajectory.
SHEN Bin, YANG Hao, XUE Zhejing, LI Wei, CHENG Feng, LU Lu, WU Jie   +6 more
doaj   +1 more source

Radial Bearings with Porous Elements

Procedia Engineering, 2016
AbstractThis paper presents the analytical model of the radial bearing of the finite length with the two-layer porous insert obtained on the basis of the dimensionless equations of movement of a viscous incompressible lubricant in an operating clearance and in porous layers of a bearing sleeve and continuity equations as well. We are analyzing the case
openaire   +1 more source

Triangular Index Ratio as an Alternative Method to the Alpha Angle for Defining the Presence of Cam Morphology: A Prospective Cohort Study

Arthritis Care &Research, EarlyView.
Objective Cam morphology, which is a significant risk factor for hip osteoarthritis, is commonly quantified by the alpha angle (AA). This study aims to explore the potential of the triangular index ratio (TIR) to quantify cam morphology on anteroposterior radiographs by assessing the association between TIR‐defined cam morphology and the development of
Jinchi Tang, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Myrthe A. van den Berg, Jos Runhaar, Sita Bierma‐Zeinstra, Rintje Agricola   +7 more
wiley   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Finite Element Analysis of Radial Bearing Magnetic Field

, 2010
There is a magnetic field inside of the radial bearing. The magnetic field distribution is one of the key factors that decides the running state and performance of the system.
Guo Qing Wu, Jing Ling Zhou, Wei Nan Zhu
core   +1 more source