Results 51 to 60 of about 313,360 (275)
Piped water cooling of concrete dams [PDF]
, 2004 Piped water is used to remove hydration heat from concrete dams during construction. By examining simple models we obtain an estimate for the temperature rise along the pipe network and within the concrete.
Ballim, Y. +5 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Radial Structure of the Internet
, 2006 The structure of the Internet at the Autonomous System (AS) level has been studied by both the Physics and Computer Science communities. We extend this work to include features of the core and the periphery, taking a radial perspective on AS network ...
Forrest, Stephanie +2 more
core +3 more sources
Analytical Formulas of Molecular Ion Abundances and N2H+ Ring in Protoplanetary Disks [PDF]
, 2015 We investigate the chemistry of ion molecules in protoplanetary disks, motivated by the detection of N$_2$H$^+$ ring around TW Hya. While the ring inner radius coincides with the CO snow line, it is not apparent why N$_2$H$^+$ is abundant outside the CO ...
Aikawa, Yuri +3 more
core +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]
, 2016 Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
core +2 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Simulation based bayesian econometric inference: principles and some recent computational advances. [PDF]
In this paper we discuss several aspects of simulation basedBayesian econometric inference. We start at an elementary level on basic concepts of Bayesian analysis; evaluatingintegrals by simulation methods is a crucial ingredientin Bayesian inference ...
Dijk, H.K. van +2 more
core +4 more sources
Identification of radial drainage networks based on topographic and geometric features
Open GeosciencesThe radial drainage network, which has a typical spatial distribution pattern, is a crucial component for reflecting regional geographical landscapes.
Liu Chengyi +5 more
doaj +1 more source