Results 61 to 70 of about 473,345 (294)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Analytic determination of high-order post-Newtonian self-force contributions to gravitational spin precession

, 2015
Continuing our analytic computation of the first-order self-force contribution to the "geodetic" spin precession frequency of a small spinning body orbiting a large (non-spinning) body we provide the exact expressions of the tenth and tenth-and-a-half ...
Bini, Donato, Damour, Thibault
core   +1 more source

Nuclear Pairing: Surface or Bulk ? [PDF]

, 2005
We analyse how the spatial localisation properties of pairing correlations are changing in a major neutron shell of heavy nuclei. It is shown that the radial distribution of the pairing density depends strongly on whether the chemical potential is close ...
A. Bohr, J. Friedel, N. Sandulescu, P. G. de Gennes, P. Noziere, P. Ring, P. Schuck, R. A. Broglia, X. Viñas   +8 more
core   +5 more sources

Mapping atomistic to coarse-grained polymer models using automatic simplex optimization to fit structural properties

, 2000
We develop coarse-grained force fields for poly (vinyl alcohol) and poly (acrylic acid) oligomers. In both cases, one monomer is mapped onto a coarse-grained bead.
Meyer, Hendrik, Mueller-Plathe, Florian, Reith, Dirk   +2 more
core   +1 more source

Conservative, gravitational self-force for a particle in circular orbit around a Schwarzschild black hole in a Radiation Gauge [PDF]

, 2011
This is the second of two companion papers on computing the self-force in a radiation gauge; more precisely, the method uses a radiation gauge for the radiative part of the metric perturbation, together with an arbitrarily chosen gauge for the parts of ...
Friedman, John, Keidl, Tobias, Kim, Dong-Hoon, Price, Larry, Shah, Abhay   +4 more
core   +2 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Systematic comparison of force fields for microscopic simulations of NaCl in aqueous solutions: Diffusion, free energy of hydration and structural properties

, 2003
In this paper we compare different force fields that are widely used (Gromacs, Charmm-22/x-Plor, Charmm-27, Amber-1999, OPLS-AA) in biophysical simulations containing aqueous NaCl.
Karttunen, Mikko, Patra, Michael
core   +1 more source

The dark matter halo shape of edge-on disk galaxies - II. Modelling the HI observations: methods [PDF]

, 2010
This is the second paper of a series in which we attempt to put constraints on the flattening of dark halos in disk galaxies. For this purpose, we observe the HI in edge-on galaxies, where it is in principle possible to measure the force field in the ...
Boulanger, de Blok, Dickey, Fall, Fraternali, Fraternali, García-Ruiz, J. C. O'Brien, K. C. Freeman, Kregel, Kregel, Lo, Mathewson, Nelder, O'Brien, Olling, P. C. van der Kruit, Petric, Rownd, Rubin, Sancisi, Shane, Shostak, Sofue, Sofue, Swaters, Takamiya, Uson, van der Kruit, van der Kruit, van der Kruit, Warmels   +31 more
core   +2 more sources

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source

Numerical Simulation Research on Radial Force of Centrifugal Pump with Guide Vanes

Shock and Vibration, 2021
To reveal the internal unsteady flow state of the guide vane centrifugal pump, in this paper, the standard SST k‐ω turbulent flow model is used for unsteady numerical simulation of the centrifugal pump.
Dongrong Meng, Ting Jiang, Hongling Deng, Gaoyang Hou   +3 more
doaj   +1 more source