Results 41 to 50 of about 121,389 (262)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Radial growth of subarctic tree and shrub species: relationships with climate and association with the greening of the forest–tundra ecotone of subarctic Québec, Canada

open access: yesArctic Science
Climate change has resulted in a widespread increase in primary productivity in northern regions. This “greening” can alter terrestrial ecosystems dynamics and trigger positive climate feedbacks but often exhibits spatial heterogeneity.
Julie-Pascale Labrecque-Foy   +3 more
doaj   +1 more source

From treeline to species line: Thermal patterns and growth relationships across the krummholz zone of whitebark pine, Sierra Nevada, California, USA

open access: yesArctic, Antarctic, and Alpine Research, 2020
A multiyear study of forest-to-alpine ecotones across extensive krummholz zones in whitebark pine (WBP; Pinus albicaulis), Sierra Nevada, California, resolved mean treeline growing season temperature (GST) of 9.3°C, 2.6°C warmer than global thresholds ...
Constance I. Millar   +2 more
doaj   +1 more source

In Vitro Effects of Leaf Extracts from Brassica rapa on the Growth of Two Entomopathogenic Fungi

open access: yesJournal of Fungi, 2021
This study aimed to determine the inhibitive or stimulatory effects of leaf extracts from two Brassica rapa subspecies on the hyphal growth of two well-known entomopathogenic fungi, Cordyceps fumosorosea and Beauveria bassiana.
Daniel G. Cerritos-Garcia   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

On radial stationary solutions to a model of non-equilibrium growth [PDF]

open access: yesEuropean Journal of Applied Mathematics, 2013
We present the formal geometric derivation of a non-equilibrium growth model that takes the form of a parabolic partial differential equation. Subsequently, we study its stationary radial solutions by means of variational techniques. Our results depend on the size of a parameter that plays the role of the strength of forcing. For small forcing we prove
Escudero, C.   +3 more
openaire   +4 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Continuum model for radial interface growth [PDF]

open access: yesPhysica A: Statistical Mechanics and its Applications, 1998
12 pages, Elsevier style, 5 ...
Batchelor, M. T.   +2 more
openaire   +2 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Impact of mistletoe attack (Viscum album ssp. abietis) on the radial growth of silver fir. A case study in the North of Eastern Carpathians [PDF]

open access: yesAnnals of Forest Research, 2009
Viscum album ssp. abietis (Wiesb.) Abrom L. is one of the three subspecies of Viscum album L that is frequently encountered in Romanian forests. The mistletoe has notoriously negative effects on trees and forests health. The mistletoe infections not only
Catalina Barbu
doaj  

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