Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The meshless radial point interpolation method for time-domain electromagnetics [PDF]
, 2008 A meshless numerical technique based on radial point interpolation is introduced for electromagnetic simulations in time domain. The general class of meshless methods presents very attractive properties for addressing future challenges of electromagnetic
Kaufmann, T. +5 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
A Meshless Radial Point Interpolation Method for Solving Fractional Navier–Stokes Equations
AxiomsThis paper aims to develop a meshless radial point interpolation (RPI) method for obtaining the numerical solution of fractional Navier–Stokes equations. The proposed RPI method discretizes differential equations into highly nonlinear algebraic equations,
Arman Dabiri +3 more
doaj +1 more source
Comparative modelling of crack propagation in elastic–plastic materials using the meshfree local radial basis point interpolation method and eXtended finite-element method [PDF]
Royal Society Open Science, 2019 The modelling and understanding of crack propagation for elastic–plastic materials is critical in various engineering applications, such as safety analysis of concrete structures and stability analysis of rock slopes.
Yazhe Li +3 more
doaj +1 more source
A new approach for the generation of real-time GNSS low-latitude ionospheric scintillation maps
Journal of Space Weather and Space Climate, 2023 Ionospheric scintillation disturbs radio frequency signals affecting navigation based on Global Navigation System (GNSS), especially in Brazil, due to the large magnetic declination.
Martinon André R. F. +2 more
doaj +1 more source
An enriched radial point interpolation method based on weak-form and strong-form\ud
, 2011 In this article, an enriched radial point interpolation method (e-RPIM) is developed for computational mechanics. The conventional radial basis function (RBF) interpolation is novelly augmented by the suitable basis functions to reflect the natural ...
Gu, YuanTong, Y. T. Gu
core +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Compressor performance modelling method based on support vector machine nonlinear regression algorithm [PDF]
Royal Society Open Science, 2020 To overcome the difficulty of having only part of compressor characteristic maps including on-design operating point, and accurately calculate compressor thermodynamic performance under variable working conditions, this paper proposes a novel compressor ...
Yulong Ying +3 more
doaj +1 more source