Results 41 to 50 of about 288,333 (267)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Reversible reddish skin color change in a patient with compressive radial neuropathy

BMC Neurology, 2018
Background The motor and sensory symptoms caused by compressive radial neuropathy are well-known, but the involvement of the autonomic nervous system or the dermatologic symptoms are less well known.
Jong Hyeon Ahn, Dae Joong Kim, Jung-Joon Sung, Yoon-Ho Hong, Suk-Won Ahn, Jeong Jin Park, Byung-Nam Yoon   +6 more
doaj   +1 more source

CFD-Based Determination of the Optimal Blowing and Suction Air Volume Ratio of Dual-Radial Swirl Shielding Ventilation in a Fully Mechanized Excavation Face

Geofluids, 2021
Dust is one of the main pollutants in coal mines, which seriously affects the physical and mental health of workers, as well as the safe production in underground mines.
Kuan Wu, Shiliang Shi, Yijie Shi, Yong Chen   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Test methods for evaluation of balloon expandable vascular stents – measurement of radial strength and stiffness

Current Directions in Biomedical Engineering, 2023
The radial strength of balloon expandable stents represents a key property for a successful recanalization of sclerotic blood vessels. This study focuses on the most commonly used method for investigation of radial strength and radial stiffness via ...
Brandt-Wunderlich Christoph, Schmidt Wolfram, Thiesen Alexander, Reinhardt Falk, Stiehm Michael, Schmitz Klaus-Peter, Siewert Stefan   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Hydraulic characterization of laterals as applied to selected radial collector wells at Belgrade groundwater source [PDF]

Geološki Anali Balkanskoga Poluostrva, 2016
The paper examines the possibility of hydraulic characterization of radial well laterals in a manner that does not require prior hydrodynamic analysis by simulating groundwater extraction conditions on a numerical model.
Polomčić Dušan, Božović Đorđije, Bajić Dragoljub   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source