Results 111 to 120 of about 168,620 (333)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Journal of Daylighting, 2020 This study aims to determine the optimum size of windows based on the window-to-floor ratio (WFR) for the main cardinal directions in Hot-summer Mediterranean (Csa) and Dry Summer Continental (Dsa) climates (Köppen–Geiger classification system) by ...
Farzam Kharvari
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Biophysical climate mitigation potential of coniferous forests in temperate ecosystems of South Tyrol [PDF]
GeoreviewForests affect climate parameters through impacts from biochemical and biophysical processes. However, the effects of the coniferous stands on hydrological setting in temperate regions have received little attention.
Polina LEMENKOVA
doaj +1 more source
Sun and Lightning: The Visibility of Radiance [PDF]
, 2016 A long chapter for The War of Appearances: Transparency, Opacity, Radiance (V2_Publishing, 2016) building on the findings of “Charis and Radiance,” an essay published two years earlier. It discusses the inherent connection between visibility and radiance
Lars, Spuybroek
core +1 more source
A new hybrid geometrical optics and radiance based scattering model for ray tracing applications [PDF]
, 2005 This paper presents a new hybrid geometrical optics (GO) and radiance based rough surface scattering model for use in ray tracing propagation models. The reflectance model includes the effects of both specular and diffuse reflection.
Ng, KH, Nix, AR, Tameh, EK
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Ground support data from July 10 to July 29, 1978, for HCMM thermal satellite data of the Powder River Basin, Wyoming [PDF]
Radiometric and meteorological data acquired at three ground stations located approximately 150 km apart in the Powder River Basin, Wyoming, are summarized.
Hummer-Miller, S. +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source