Results 41 to 50 of about 3,644,479 (344)
Radiation-induced kidney toxicity: molecular and cellular pathogenesis
Radiation Oncology, 2021 Radiation nephropathy (RN) is a kidney injury induced by ionizing radiation. In a clinical setting, ionizing radiation is used in radiotherapy (RT).
Richard Klaus +2 more
semanticscholar +1 more source
Parent‐to‐Child Information Disclosure in Pediatric Oncology
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor +12 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura +5 more
wiley +1 more source
Molecular Mechanisms of Radiation-Induced Cancer Cell Death: A Primer
Frontiers in Cell and Developmental Biology, 2020 Radiation therapy (RT) is responsible for at least 40% of cancer cures, however treatment resistance remains a clinical problem. There have been recent advances in understanding the molecular mechanisms of radiation-induced cell death.
J. Sia, Radosław Szmyd, E. Hau, H. Gee
semanticscholar +1 more source
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Modification of Aerosol Gold Nanoparticles by Nanosecond Pulsed-Periodic Laser Radiation [PDF]
, 2021 Kirill Khabarov +5 more
openalex +1 more source
Cancer and Radiation Therapy: Current Advances and Future Directions
International Journal of Medical Sciences, 2012 In recent years remarkable progress has been made towards the understanding of proposed hallmarks of cancer development and treatment. However with its increasing incidence, the clinical management of cancer continues to be a challenge for the 21st ...
R. Baskar, Kuo Ann Lee, R. Yeo, K. Yeoh
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker +7 more
wiley +1 more source
Water Vapor Spectroscopy and Thermodynamics Constrain Earth's Tropopause Temperature
AGU AdvancesAs Earth warms, the tropopause is expected to rise, but predictions of its temperature change are less certain. Longstanding theories employing “gray” radiation tie the tropopause temperature to outgoing longwave radiation (OLR), but this is in contrast ...
Brett A. McKim +3 more
doaj +1 more source
Silybin Derivatives Produced by γ-Irradiation and Their Tyrosinase Inhibitory Activities
MoleculesSilybin, which belongs to the flavonolignan group, is the major component of the fruit extract of Silybum marianum (common name: milk thistle). Silybin is a medicinal compound with hepatoprotective, antioxidant, and anticancer properties.
Ah-Reum Han +2 more
doaj +1 more source