Results 51 to 60 of about 3,524,646 (254)
The Pressure of Radiation [PDF]
WITH reference to my letter on this subject in NATURE of December 18, the majority of my correspondents complain that, although I may have indicated the possibility of my own view, I have not shown why the simpler relation, that the pressure is always one-third of the energy density, is untenable. As I cannot reply to each individually, I shall be glad
openaire +2 more sources
Radiation hydrodynamics including irradiation and adaptive mesh refinement with AZEuS. I. Methods
Aims. The importance of radiation to the physical structure of protoplanetary disks cannot be understated. However, protoplanetary disks evolve with time, and so to understand disk evolution and by association, disk structure, one should solve the ...
Dullemond, C. P., Ramsey, J. P.
core +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
The properties of radiation created by a classical ultrarelativistic scalar charged particle in a constant homogeneous crossed electromagnetic field are described both analytically and numerically with radiation reaction taken into account in the form of
Bogdanov, O. V.+2 more
core +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Introduction to Special Issue on Radiation Effects [PDF]
[Excerpt] How dangerous is radiation? How much radiation does it take to give us cancer? Are we wasting money on overly restrictive regulations, or are we not being sufficiently protective of our radiation workers and the public?
Karam, P. Andrew
core +1 more source
Emergent Radiation in an Atom-Field System at Twice-Resonance
A two-level atom interacting with a single mode of quantized electromagnetic radiation is discussed using a representation in which the atom and the radiation are unified into a {\em new} canonical radiation.
Brennen G K+4 more
core +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source