Results 51 to 60 of about 1,817,208 (305)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Optimizing radiation therapy treatments by exploring tumour ecosystem dynamics in-silico [PDF]
, 2019 In this contribution, we propose a system-level compartmental population dynamics model of tumour cells that interact with the patient (innate) immune system under the impact of radiation therapy (RT).
Fellermann, Harold, Scheidegger, Stephan
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Chinese Medicine, 2020 Background Ophiocordyceps sinensis, which is only naturally found in the high-elevation extreme environment of the Tibetan Plateau, has been used in traditional Chinese medicine. Information concerning the evolutionary and geologic context of O. sinensis
Jie Liu +11 more
doaj +1 more source
A Theoretical Sub-0.1 dB Loss Single Mode Fiber-To-Chip Edge Coupler for Silicon Nitride Waveguides
Photonics, 2023 A low loss optical interconnection between optical fibers and photonic integrated circuits is critical for high performance photonic systems. In the past decade, spot size converters, subwavelength waveguide grating (SWG) structures, and different ...
Di Wu +7 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Радиационная гигиенаThe artilcle presents comments on the manuscript by A.S. Vasiliev et al. “A review of approaches to assessment of potential radon hazard of land plots”.
P. S. Miklyaev +2 more
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Detection of Polonium-210 in Environmental, Biological and Food Samples: A Review
Molecules, 2023 Ingestion of polonium-210 from environmental media and food can cause serious health hazards (e.g., gastrointestinal symptoms, tumours, etc.) and has been a public health concern worldwide since the 2006 poisoning of Agent Litvinenko 210Po in Russia ...
Lei Zhou +4 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Contamination control handbook [PDF]
, 1968 Contamination Control Handbook provides technical information on avoiding contamination of physical, chemical or biological systems or products. The book includes control methods for product design, gases and liquids, airborne and surface contamination ...
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THE DETERMINATION OF 89SR ACTIVITY IN OBJECTS OF ENVIRONMENT
Радиационная гигиена, 2016 The radionuclide 89Sr give considerable contribution in the composition of fission products, which get in environment due to an accident of nuclear reactor or due to conducting of peaceful nuclear explosion. By radiation characteristics this radionuclide
O. N. Prokof 'ev
doaj