Results 41 to 50 of about 138,699 (259)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Radiation exposure of a mobile 3D C-arm with large flat-panel detector for intraoperative imaging and navigation - an experimental study using an anthropomorphic Alderson phantom

open access: yesBMC Medical Imaging, 2020
Background Intraoperative 3-dimensional (3D) navigation is increasingly being used for pedicle screw placement. For this purpose, dedicated mobile 3D C-arms are capable of providing intraoperative fluoroscopy-based 3D image data sets.
Yashar Naseri   +5 more
doaj   +1 more source

Calculation of NaI(Tl) detector efficiency using 226Ra, 232Th, and 40K radioisotopes: Three-phase Monte Carlo simulation study

open access: yesOpen Chemistry, 2022
Thallium-activated sodium iodide (NaI(Tl)) detectors can be used in gamma cameras, environmental radiation assessments, including radiation emission levels from nuclear reactors, and radiation analysis equipment.
Tekin Huseyin Ozan   +5 more
doaj   +1 more source

Cl-Doped CdTe Crystal Growth for Medical Imaging Applications

open access: yesCrystals, 2022
CdTe:Cl doped single crystals were grown under conditions of tellurium excess by using an accelerated crucible rotation technique, modified vertical Bridgman (ACRT-MVB) method.
Rubi Gul   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Simulation nuclear signal generation program based on convolution model

open access: yes四川大学学报. 自然科学版, 2023
Due to the advantages of high detection efficiency and low cost, NaI(Tl) detectors are often used in the fields of nuclear radiation energy spectrum measurement and nuclear radiation supervision.
SHAO Wei-Hao   +4 more
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Nature of spontaneous signal and detection of radiation emitted from hydrogen Rydberg matter

open access: yesAIP Advances
In this article, we report on laser-induced radiation and spontaneous radiation emitted from a chamber containing hydrogen Rydberg matter. The emitted isotropic radiation penetrates a 3-mm-thick steel wall and several meters of air.
S. A. Zeiner-Gundersen, S. Olafsson
doaj   +1 more source

Reference based simulation study of detector comparison for BNCT-SPECT imaging

open access: yesNuclear Engineering and Technology, 2020
To investigate the optimal detector material for prompt gamma imaging during boron neutron capture therapy, in this study, we evaluated the characteristic regarding radiation reaction of available detector materials using a Monte Carlo simulation ...
Moo-Sub Kim   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy