Results 61 to 70 of about 2,373,663 (375)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Method for analyzing radiation sensitivity of integrated circuits [PDF]

open access: yes, 1979
A method for analyzing the radiation sensitivity of an integrated circuit is described to determine the components. The application of a narrow radiation beam to portions of the circuit is considered.
Gauthier, M. K., Stanley, A. G.
core   +1 more source

Dosimetric Analysis of Neural and Vascular Structures in Skull Base Tumors Treated with Stereotactic Radiosurgery. [PDF]

open access: yes, 2017
Objective To examine the relationship between the prescribed target dose and the dose to healthy neurovascular structures in patients with vestibular schwannomas treated with stereotactic radiosurgery (SRS).
Bhatt, Jay M   +6 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Evaluation of Image Quality and Radiation Dose in Upgraded Analog Radiographic Systems Using the Contrast Detail Radiography (CDRAD) Phantom

open access: yesمجله دانشکده پزشکی اصفهان, 2020
Background: Upgrading analog X-ray systems to digital systems will greatly reduce costs, but there are conflicting opinions on this subject. Therefore, the purpose of this study was to compare image quality and radiation dose in different upgraded analog
Mohammad Reza Choopani, Ali Chapaian
doaj   +1 more source

Measurement and Protection of Induced Radioactivity in Proton Heavy Ion Accelerator Therapy

open access: yesJournal of Isotopes, 2021
Proton-heavy ion therapy is internationally recognized as the most advantageous radiotherapy method in oncology. However, due to the relatively high energy of the proton-heavy ion beams, the secondary neutrons produced in the process of beam energy loss ...
HU Qisheng;YANG Jun
doaj   +1 more source

Thoracic radiation therapy: dosage and techniques [PDF]

open access: yesLung Cancer, 1989
Combination chemotherapy (CC) deserves credit for the increase in survival for patients with limited small cell lung cancer (SCLC). However, the best CC is not clearly established. The definition of limited disease and the work-up to define limited disease has evolved over the last 20 years.
openaire   +3 more sources

High Efficiency Positron Accumulation for High-Precision Measurements

open access: yes, 2014
Positrons are accumulated within a Penning trap designed to make more precise measurements of the positron and electron magnetic moments. The retractable radioactive source used is weak enough to require no license for handling radioactive material and ...
E. Novitski   +4 more
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Exploration of clinical preferences in treatment planning of radiotherapy for prostate cancer using Pareto fronts and clinical grading analysis

open access: yesPhysics and Imaging in Radiation Oncology, 2020
Introduction: Radiotherapy treatment planning is a multi-criteria problem. Any optimization of the process produces a set of mathematically optimal solutions.
A. Kyroudi   +5 more
doaj  

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