Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Radiation Medicine and ProtectionObjective: To explore the new treatment strategies for radiation proctitis, which is the most common complication of pelvic tumor malignancies. Methods: Four cases of patients with severe radiation proctitis were treated with high-dosage vitamin C (VC ...
Han Wu +6 more
doaj +1 more source
Study of early nausea and vomiting response of swine to ionizing radiation Final technical progress report, 15 Sep. - 12 Dec. 1969 [PDF]
Early nausea and vomiting response of swine to ionizing radiation related to radiation dosage and effect on humans in space ...
Sullivan, M. F.
core +1 more source
Survival of dental implants in patients with oral cancer treated by surgery and radiotherapy: a retrospective study [PDF]
, 2015 BACKGROUND: The aim of this retrospective study was to evaluate the survival of dental implants placed after ablative surgery, in patients affected by oral cancer treated with or without radiotherapy.
A Agresti +37 more
core +2 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Colonic stenting for colorectal cancer: stoma avoidance with acceptable radiation exposure [PDF]
Clinical EndoscopyBackground/Aims Self-expanding metal stents (SEMS) are used to manage colonic obstruction for palliative decompression or as a bridge to curative surgery and are typically placed under fluoroscopic guidance.
Christopher Robert Smith +5 more
doaj +1 more source
A preliminary analysis of the radiation burden of a typical Mars lander mission [PDF]
Predicted radiation dosage for Mars lander ...
Dugan, V. L.
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Windows Setting for Low kVp Abdominal CT: Comparison to 120-kVp CT Images
대한영상의학회지, 2017 Purpose: The purpose of the study is to identify the optimal window level (WL) and window width (WW) to maximize visualization of the findings for low kVp abdominal CT images utilizing the automated tube voltage selection (ATVS) (which ...
Jun Sung Kim +7 more
doaj +1 more source
Optimization of Retrospective Gated-ECG Coronary Computed Tomography Angiography by Dose Reduction in Patients with Different Body Mass Indexes [PDF]
Journal of Biomedical Physics and EngineeringBackground: The reduction of patient radiation dose in coronary Computed Tomography Angiography (CCTA) with acceptable image quality is considered an important factor in the research.Objective: This study aims to optimize the CCTA protocol using a ...
Behzad Fazlkhah +5 more
doaj +1 more source