Results 61 to 70 of about 1,545,857 (315)
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Radiation exposure in emergency ureteric stenting: A subgroup analysis by operator
BJUI Compass, 2023 Objectives To review radiation exposure during emergency ureteric stent insertion to identify differences based on operator experience, specialty operator and stone characteristics.
Kevin Tree +5 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Dose optimization to minimize radiation risk with acceptable image quality [PDF]
, 2021 Image quality has been found to be positively correlated with diagnosis accuracy. Radiologist aim for the highest quality image possible to determine the location of the suspected pathology.
Ji, Chuncheng
core +1 more source
eJournal of Oral Maxillofacial Research, 2013 Objectives: Efforts are made in radiographic examinations to obtain the best image quality with the lowest possible absorbed dose to the patient. In dental radiography, the absorbed dose to patients is very low, but exposures are relatively frequent.
Kristina Hellén-Halme, Mats Nilsson
doaj +1 more source
University of California Radiation Laboratory Reports UCRL-1729
, 1952 Quarterly summary report of studies conducted through the Radiation Laboratory, University of California.
Lawrence Radiation Laboratory
core
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Effective Dose in Abdominal Digital Radiography: Patient Factors
대한영상의학회지, 2017 Purpose To identify independent patient factors associated with an increased radiation dose, and to evaluate the effect of patient position on the effective dose in abdominal digital radiography.
Ji Sung Jang +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Radiation Medicine and ProtectionObjective: To explore the new treatment strategies for radiation proctitis, which is the most common complication of pelvic tumor malignancies. Methods: Four cases of patients with severe radiation proctitis were treated with high-dosage vitamin C (VC ...
Han Wu +6 more
doaj +1 more source