Results 71 to 80 of about 12,335,562 (261)

The study of neutron sensitivity of the MCP based on recoil proton detection

open access: yesAIP Advances, 2020
A new neutron detector based on a recoil proton and a microchannel plate (MCP) has been developed for the measurement of ultrafast pulse neutrons.
Xiaodong Zhang   +7 more
doaj   +1 more source

University of California Radiation Laboratory Reports UCRL-1632

open access: yes, 1952
Quarterly summary report of studies conducted through the Radiation Laboratory, University of California.
University of California. Radiation Laboratory.
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

University of California Radiation Laboratory Reports UCRL-1610

open access: yes, 1951
Quarterly summary report of studies conducted through the Radiation Laboratory, University of California.
University of California. Radiation Laboratory.
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Investigating the influence of the wire-arrays’ electrical parameters on the load current of the z-pinch drivers

open access: yesAIP Advances, 2020
Wire arrays are the typical loads which have been widely used in z-pinch research studies. When a large pulsed power accelerator is designed, the electrical parameters of the z-pinch loads including the inductance and the resistance (or the equivalent ...
Liangping Wang   +4 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Parallel-Channel PIV System for Time-Resolved Measurement of Shock Wave Reflection and Diffraction

open access: yesSensors
Conventional particle image velocimetry (PIV) techniques face an inherent trade-off between temporal resolution and single-pulse laser energy, limiting their performance in shock wave measurements.
Tianqing Zhao   +5 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Theoretical and experimental study of the dark signal in CMOS image sensors affected by neutron radiation from a nuclear reactor

open access: yesAIP Advances, 2017
The CMOS image sensors (CISs) are irradiated with neutron from a nuclear reactor. The dark signal in CISs affected by neutron radiation is studied theoretically and experimentally.
Yuanyuan Xue   +8 more
doaj   +1 more source

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