Results 111 to 120 of about 2,082,361 (307)

Salen Mn Complexes Mitigate Radiation Injury in Normal Tissues [PDF]

, 2011
Salen Mn complexes, including EUK-134, EUK-189 and a newer cyclized analog EUK-207, are synthetic SOD/catalase mimetics that have beneficial effects in many models of oxidative stress.
Doctrow, Susan R., Fish, Brian, Hill, Richard P., Huffman, Karl D., Lazarova, Zelmira, Mahmood, Javed, Medhora, Meetha, Molthen, Robert C., Moulder, John E., Rosenthal, Rosalind A., Sonis, Stephen T., Tofilon, Philip J.   +11 more
core   +2 more sources

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Limitations of serial cloning in mammals

Nature Communications
Mammals can now be cloned artificially, but it remains unknown whether they can also maintain their species through cloning. Herein, we continued serial cloning for 20 years from a single donor mouse.
Sayaka Wakayama, Daiyu Ito, Rei Inoue, Masatoshi Ooga, Masaaki Toshishige, Yasunari Satoh, Hirosuke Shiura, Takashi Kohda, Arikuni Uchimura, Teruhiko Wakayama   +9 more
doaj   +1 more source

A summary of UNSCEAR evaluation on medical exposure to ionizing radiation and call for more representative data

Radiation Medicine and Protection
The annex A of the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) 2020/2021 Report presented a comprehensive global estimate of frequencies and doses from medical exposure to ionizing radiation, their distribution and ...
Jing Chen
doaj   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Numerical calculations of a high brilliance synchrotron source and on issues with characterizing strong radiation damping effects in non-linear Thomson/Compton backscattering experiments

, 2012
A number of theoretical calculations have studied the effect of radiation reaction forces on radiation distributions in strong field counter-propagating electron beam-laser interactions, but could these effects - including quantum corrections - be ...
Bulanov, S. S., Griffin, B. J., Mangles, S. P. D., Ridgers, C. P., Thomas, A. G. R.   +4 more
core  

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

RENEB interlaboratory comparison for biological dosimetry based on dicentric chromosome analysis and cobalt-60 exposures higher than 2.5 Gy

Scientific Reports
In previous RENEB interlaboratory comparisons based on the manual scoring of dicentric chromosomes, a tendency for systematic overestimation for doses > 2.5 Gy was found.
Martin Bucher, David Endesfelder, Stefan Pojtinger, Ans Baeyens, Joan-Francesc Barquinero, Christina Beinke, Laure Bobyk, Eric Gregoire, Rositsa Hristova, Juan S. Martinez, Prabodha Kumar Meher, Marcela Milanova, Octávia Monteiro Gil, Alegria Montoro, Jayne Moquet, Mercedes Moreno Domene, María Jesús Prieto, Monica Pujol-Canadell, Mingzhu Sun, Georgia I. Terzoudi, Ales Tichy, Sotiria Triantopoulou, Marco Valente, Anne Vral, Andrzej Wojcik, Ursula Oestreicher   +25 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source