Results 11 to 20 of about 718,807 (247)

Isolation of five different primary cell types from a single sample of human skin

STAR Protocols, 2022
Summary: We have developed a technique to isolate primary keratinocytes, melanocytes, fibroblasts, preadipocytes, and microvascular endothelial cells from an individual sample of human skin. The protocol describes step-by-step instructions for processing,
Sylwia Kabacik, Donna Lowe, Howard Cohen, Sarah Felton, Joseph Spitzer, Ken Raj   +5 more
doaj   +1 more source

Oxidative Stress and X-ray Exposure Levels-Dependent Survival and Metabolic Changes in Murine HSPCs

Antioxidants, 2021
Haematopoietic bone marrow cells are amongst the most sensitive to ionizing radiation (IR), initially resulting in cell death or genotoxicity that may later lead to leukaemia development, most frequently Acute Myeloid Leukaemia (AML).
Melis Karabulutoglu, Rosemary Finnon, Lourdes Cruz-Garcia, Mark A. Hill, Christophe Badie   +4 more
doaj   +1 more source

Nuclear Fragility in Radiation-Induced Senescence: Blebs and Tubes Visualized by 3D Electron Microscopy

Cells, 2022
Irreparable DNA damage following ionizing radiation (IR) triggers prolonged DNA damage response and induces premature senescence. Cellular senescence is a permanent state of cell-cycle arrest characterized by chromatin restructuring, altered nuclear ...
Benjamin M. Freyter, Mutaz A. Abd Al-razaq, Anna Isermann, Anne Dietz, Omid Azimzadeh, Liesbeth Hekking, Maria Gomolka, Claudia E. Rübe   +7 more
doaj   +1 more source

Japanese Legacy Cohorts: The Life Span Study Atomic Bomb Survivor Cohort and Survivors’ Offspring

Journal of Epidemiology, 2018
Cohorts of atomic bomb survivors—including those exposed in utero—and children conceived after parental exposure were established to investigate late health effects of atomic bomb radiation and its transgenerational effects by the Atomic Bomb Casualty ...
Kotaro Ozasa, Eric J Grant, Kazunori Kodama   +2 more
doaj   +1 more source

The Protection Effect of Resveratrol Against Radiation-Induced Inflammatory Bowel Disease via NLRP-3 Inflammasome Repression in Mice

Dose-Response, 2020
With the extensive application of radiotherapy in various cancers, its side effects in tissues adjacent to cancers are garnering much attention. Intestines are sensitive to irradiation due to its rapid proliferation, and irradiation-induced enteric ...
Hao Sun, Hui Cai, Yue Fu, Qin Wang, Kaihua Ji, Liqing Du, Chang Xu, Lifang Tian, Ningning He, Jinhan Wang, Manman Zhang, Yang Liu, Yan Wang, Jia Li, Qiang Liu   +14 more
doaj   +1 more source

Two New Potential Therapeutic Approaches in Radiation Cystitis Derived from Mesenchymal Stem Cells: Extracellular Vesicles and Conditioned Medium

Biology, 2022
Background: Radiation cystitis (RC) results from chronic inflammation, fibrosis, and vascular damage. The urinary symptoms it causes have a serious impact on patients’ quality of life.
Carole Helissey, Nathalie Guitard, Hélène Théry, Sylvie Goulinet, Philippe Mauduit, Maria Girleanu, Anne-Laure Favier, Michel Drouet, Charles Parnot, Cyrus Chargari, Sophie Cavallero, Sabine François   +11 more
doaj   +1 more source

Association Between Prevalence of Peripheral Artery Disease and Radiation Exposure in the Atomic Bomb Survivors

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Past reports suggested that total‐body irradiation at 0.5 to 1.0 Gy could be responsible for atherosclerosis. Peripheral artery disease (PAD) is a manifestation of systematic atherosclerosis.
Ikuno Takahashi, John Cologne, Daisuke Haruta, Michiko Yamada, Tetsuya Takahashi, Munechika Misumi, Saeko Fujiwara, Masayasu Matsumoto, Yasuki Kihara, Ayumi Hida, Waka Ohishi   +10 more
doaj   +1 more source

Chronic Inflammation and Radiation-Induced Cystitis: Molecular Background and Therapeutic Perspectives

Cells, 2020
Radiation cystitis is a potential complication following the therapeutic irradiation of pelvic cancers. Its clinical management remains unclear, and few preclinical data are available on its underlying pathophysiology.
Carole Helissey, Sophie Cavallero, Clément Brossard, Marie Dusaud, Cyrus Chargari, Sabine François   +5 more
doaj   +1 more source

Historical Changes in Histological Diagnosis of Lung Cancer

Journal of Epidemiology, 2019
Background: Histological classification of lung cancer is essential for investigations of carcinogenesis and treatment selection. We examined the temporal changes of lung cancer histological subtypes. Methods: Lung cancer cases diagnosed in the Life Span
Mai Utada, Shuji Yonehara, Kotaro Ozasa
doaj   +1 more source

Dose Variations Using an X-Ray Cabinet to Establish in vitro Dose-Response Curves for Biological Dosimetry Assays

Frontiers in Public Health, 2022
In biological dosimetry, dose-response curves are essential for reliable retrospective dose estimation of individual exposure in case of a radiation accident.
Martin Bucher, Tina Weiss, David Endesfelder, Francois Trompier, Yoann Ristic, Patrizia Kunert, Helmut Schlattl, Augusto Giussani, Ursula Oestreicher   +8 more
doaj   +1 more source