Results 21 to 30 of about 2,065,180 (198)

Two New Potential Therapeutic Approaches in Radiation Cystitis Derived from Mesenchymal Stem Cells: Extracellular Vesicles and Conditioned Medium

Biology, 2022
Background: Radiation cystitis (RC) results from chronic inflammation, fibrosis, and vascular damage. The urinary symptoms it causes have a serious impact on patients’ quality of life.
Carole Helissey, Nathalie Guitard, Hélène Théry, Sylvie Goulinet, Philippe Mauduit, Maria Girleanu, Anne-Laure Favier, Michel Drouet, Charles Parnot, Cyrus Chargari, Sophie Cavallero, Sabine François   +11 more
doaj   +1 more source

Historical Changes in Histological Diagnosis of Lung Cancer

Journal of Epidemiology, 2019
Background: Histological classification of lung cancer is essential for investigations of carcinogenesis and treatment selection. We examined the temporal changes of lung cancer histological subtypes. Methods: Lung cancer cases diagnosed in the Life Span
Mai Utada, Shuji Yonehara, Kotaro Ozasa
doaj   +1 more source

Chronic Inflammation and Radiation-Induced Cystitis: Molecular Background and Therapeutic Perspectives

Cells, 2020
Radiation cystitis is a potential complication following the therapeutic irradiation of pelvic cancers. Its clinical management remains unclear, and few preclinical data are available on its underlying pathophysiology.
Carole Helissey, Sophie Cavallero, Clément Brossard, Marie Dusaud, Cyrus Chargari, Sabine François   +5 more
doaj   +1 more source

Dose Variations Using an X-Ray Cabinet to Establish in vitro Dose-Response Curves for Biological Dosimetry Assays

Frontiers in Public Health, 2022
In biological dosimetry, dose-response curves are essential for reliable retrospective dose estimation of individual exposure in case of a radiation accident.
Martin Bucher, Tina Weiss, David Endesfelder, Francois Trompier, Yoann Ristic, Patrizia Kunert, Helmut Schlattl, Augusto Giussani, Ursula Oestreicher   +8 more
doaj   +1 more source

Post-Irradiation Thymic Regeneration in B6C3F1 Mice Is Age Dependent and Modulated by Activation of the PI3K-AKT-mTOR Pathway

Biology, 2022
The risk of radiation-induced carcinogenesis depends on age at exposure. We previously reported principal causative genes in lymphomas arising after infant or adult exposure to 4-fractionated irradiation as Pten or Ikzf1, respectively, suggesting that ...
Masaaki Sunaoshi, Benjamin J. Blyth, Yi Shang, Chizuru Tsuruoka, Takamitsu Morioka, Mayumi Shinagawa, Mari Ogawa, Yoshiya Shimada, Akira Tachibana, Daisuke Iizuka, Shizuko Kakinuma   +10 more
doaj   +1 more source

Cosmic optical activity from an inhomogeneous Kalb-Ramond field [PDF]

, 2001
The effects of introducing a harmonic spatial inhomogeneity into the Kalb-Ramond field, interacting with the Maxwell field according to a `string-inspired' proposal made in earlier work are investigated.
Das P, Green M, Kar S, Majumdar P, Parthasarathi Majumdar, Saurabh Sur, Sayan Kar, Soumitra Sen Gupta   +7 more
core   +2 more sources

ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response

Radiation Oncology, 2022
Background The DNA damage response (DDR) is a mechanism that protects cells against radiation-induced oxidative DNA damage by causing cell cycle arrest and apoptosis. TP63 is a member of the tumour suppressor TP53 gene family, and ΔNp63α, a TP63 splicing
Ken-ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Daisuke Iizuka, Misaki Sugai-Takahashi, Moe Muramatsu, Akira Sakai   +7 more
doaj   +1 more source

COVID-19-Associated Pneumonia: Radiobiological Insights

Frontiers in Pharmacology, 2021
The evolution of SARS-CoV-2 pneumonia to acute respiratory distress syndrome is linked to a virus-induced “cytokine storm”, associated with systemic inflammation, coagulopathies, endothelial damage, thrombo-inflammation, immune system deregulation and ...
Sabine François, Carole Helissey, Sophie Cavallero, Michel Drouet, Nicolas Libert, Jean-Marc Cosset, Eric Deutsch, Eric Deutsch, Lydia Meziani, Lydia Meziani, Cyrus Chargari, Cyrus Chargari, Cyrus Chargari   +12 more
doaj   +1 more source

Effects of Omitting Non-confounding Predictors From General Relative-Risk Models for Binary Outcomes

Journal of Epidemiology, 2019
Background: The effects, in terms of bias and precision, of omitting non-confounding predictive covariates from generalized linear models have been well studied, and it is known that such omission results in attenuation bias but increased precision with ...
John Cologne, Kyoji Furukawa, Eric J. Grant, Robert D. Abbott   +3 more
doaj   +1 more source

Critical Review on Toxicological Mechanisms Triggered by Inhalation of Alumina Nanoparticles on to the Lungs

Biomedicines, 2022
Alumina nanoparticles (Al2O3 NPs) can be released in occupational environments in different contexts such as industry, defense, and aerospace. Workers can be exposed by inhalation to these NPs, for instance, through welding fumes or aerosolized ...
Samir Dekali, Alexandra Bourgois, Sabine François   +2 more
doaj   +1 more source